Passionate polymer chemist and biomaterial scientist specialized in developing lipid or polymer-based formulations for oligonucleotides delivery, drug delivery, and implantable biosensor.
· Yu Zhang, Duo An, Yehudah Pardo, Alan Chiu, Wei Song, Qingsheng Liu, Fang Zhou, Sean P. McDonough, Minglin Ma*. A drip-crosslinked tough hydrogel. Polymer. 2018; 135: 327-330.
· Liu, Qingsheng; An, Duo; Chiu, Alan; Li, Wenchen; Chen, Esther Y; Wang, Longhai; Zhang, Yu; Pardo, Yehudah ; McDonough, Sean; Liu, Lingyun; Liu, Wendy; Ma, Minglin*, A new class of mechanically robust triazole-zwitterionic hydrogels with foreign body response (FBR)-resistant property. In press.
· Yu Zhang, Xin Chen, Chunsheng Xiao*, Mingqiang Li, Jianxun Ding, Xiuli Zhuang, Xuesi Chen*. Co-delivery of CPT and DOX in a “two-in-one” prodrug to promote tumor suppression efficiency. In press.
· Yu Zhang，Chunsheng Xiao*, Xin Chen, Mingqiang Li, Xiuli Zhuang, Xuesi Chen*. Toothbrush like polypeptide-based copolymers for tumor environment pH sensitive drug delivery. In press.
· Yu Zhang, Duo An, Yehudah Pardo, Alan Chiu, Wei Song, Qingsheng Liu, Fang Zhou, Sean P. McDonough, Minglin Ma*. High-water-content and resilient PEG-containing hydrogels with low fibrotic response. Acta Biomaterialia. 2017; 53: 100-108.
· Yu Zhang, Minglin Ma. “Microscale Cell Encapsulation Materials and Fabrication Techniques for Type 1 Diabetes” for the book “Microscale Technologies for Cellular Engineering”. Publisher: Springer, 2016, (Book Chapter)
· Yu Zhang, Jianxun Ding, Mingqiang Li, Xin Chen, Chunsheng Xiao*, Xiuli Zhuang, Yubin Huang, Xuesi Chen*. One-Step “Click Chemistry”-Synthesized Cross-Linked Prodrug Nanogel for Highly Selective Intracellular Drug Delivery and Upregulated Antitumor Efficacy. ACS applied materials & interfaces. 2016; 8: 10673-10682.
· Yu Zhang, Chunsheng Xiao, Jianxun Ding, Mingqiang Li, Xin Chen, Zhaohui Tang, Xiuli Zhuang, Xuesi Chen*. A comparative study of linear, Y-shaped and linear-dendritic methoxy poly(ethylene glycol)-b-polyamidoamine-b-poly(L-glutamic acid) block copolymers for doxorubicin delivery in vitro and in vivo. Acta Biomaterialia. 2016; 40: 243-253.
· Yu Zhang, Duo An, Wei Song, Yehudah Pardo, Minglin Ma*. Drug-Eluting Conformal Coatings on Individual Cells. Cellular and Molecular Bioengineering (Young Innovator Award Special Issue). 2016; 9: 382-397.
· Zhiyu Zhang*, Feng Wang, Jianxun Ding, Haifei Zhang, Jiajun Zhu, Zhenguo Sun, Yu Zhang. Cationic dendron-bearing lipid/CD151 siRNA complex inhibits osteosarcoma metastasis by down-regulating matrix metalloproteinase-9. RSC advances. 2016; 6: 59601-59609.
· Mingqiang Li, Zhaohui Tang, Yu Zhang, Shixian Lv, Quanshun Li, Xuesi Chen*. Targeted delivery of cisplatin by LHRH-peptide conjugated dextran nanoparticles suppresses breast cancer growth and metastasis. Acta Biomaterialia. 2015; 18:132-143.
· Yu Zhang, Chunsheng Xiao, Mingqiang Li, Jianxun Ding, Chaoliang He, Xiuli Zhuang and Xuesi Chen*. Core-cross-linked micellar nanoparticles from linear-dendritic prodrug for dual-responsive drug delivery. Polymer Chemistry. 2014; 5 (8): 2801-2808.
Yu Zhang (firstname.lastname@example.org)
· ZHANG Yu, XIAO ChunSheng, LI MingQiang, DING JianXun, YANG ChenGuang, ZHUANG XiuLi & CHEN XueSi*. Co-delivery of doxorubicin and paclitaxel with linear-dendritic block copolymer for enhanced anti-cancer efficacy. SCIENCE CHINA Chemistry. 2014; 57 (4): 624-632.
· Mingqiang Li, Zhaohui Tang, Chao Wang, Yu Zhang, Haitao Cui, Xuesi Chen*. Efficient side-chain modification of dextran via base-catalyzed epoxide ring-opening and thiol-ene click chemistry in aqueous media. Chinese Journal of Polymer Science. 2014; 32 (8): 969-974.
· Mingqiang Li, Zhaohui Tang, Jian Lin, Yu Zhang, Shixian Lv, Wantong Song, Yubin Huang, Xuesi Chen*. Synergistic Antitumor Effects of Doxorubicin‐Loaded Carboxymethyl Cellulose Nanoparticle in Combination with Endostar for Effective Treatment of Non‐Small‐Cell Lung Cancer. Advanced Healthcare Materials. 2014; 3 (11): 1877-1888.
· Chunsheng Xiao, Yilong Cheng, Yu Zhang, Jianxun Ding, Chaoliang He, Xiuli Zhuang, Xuesi Chen*. Side chain impacts on pH- and thermo-responsiveness of tertiary amine functionali52zed polypeptides. Journal of Polymer Science, Part A. 2014;52 (5): 591-738.
· Mingqiang Li, Zhaohui Tang, Yu Zhang, Shixian Lv, Haiyang Yu, Dawei Zhang, Hua Hong, Xuesi Chen*. LHRH-peptide conjugated dextran nanoparticles for targeted delivery of cisplatin to breast cancer. Journal of Materials Chemistry B. 2014; 2 (22): 3490-3499.
· Yu Zhang, Chunsheng Xiao, Mingqiang Li, Jie Chen, Jianxun Ding, Chaoliang He, Xiuli Zhuang, Xuesi Chen*. Co-delivery of 10-Hydroxycamptothecin with Doxorubicin Conjugated Prodrugs for Enhanced Anticancer Efficacy. Macromolecular Bioscience. 2013; 13 (5): 584-594.
· Yu Zhang, Jie Chen, Chunsheng Xiao, Mingqiang Li, Huayu Tian, and Xuesi Chen*. Cationic Dendron-Bearing Lipids: Investigating Structure–Activity Relationships for Small Interfering RNA Delivery. Biomacromolecules. 2013; 14 (12): 4289-4300.
Honor and awards
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