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Dedicated R&D scientist with hands-on experience in physical characterization of biologics/materials using a broad range of analytical approaches including but not limited to spectroscopy, microscopy, bulk properties and thermal characterization. Ability to deal with large amount of data and necessary analytical/quantitative skills as documented in completed projects and published peer-reviewed articles. Team leader with proven project management skills and demonstrated ability to adjust in dynamic working environment while contributing in multiple groups, resulting in successful completion of inter-departmental projects and milestones. Self-motivated professional willing to take on new and challenging assignments and to implement new ideas or alternative solutions while taking thoughtful and timely action when confronted with problems, resulting with enhance value of undergoing projects and significant increase of the team productivity.
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- Leading physical characterizations studies; developing novel methodologies and assays for characterization of biologics, including but not limited to their physical stability, determination of particle size, thermal analysis, formulation effects and aggregation; developing SOP and protocols for assays and operation of state of the art instrumentations, resulting in growth of department with new programs.
- Independently planning, designing and conducting experiments for characterization of physical properties of biological material while managing several projects simultaneously; adapting and employing new experimental approaches as needed based on R&D needs.
- Conducting formulation studies of biologics and testing these formulations for their physical stability, including the statistical analysis and interpretation of data to drive decisions.
- Hands-on experience on planning, designing and performing/screening aggregation study of biologics, including particle sizing, protein-protein interactions and structural evaluation, using light scattering and fluorescence spectroscopy approaches.
- Developed a program for investigation of physical stability including prediction of protein- protein and protein-excipients interactions and determination of size and structure of aggregates.
- Extensive hands-on experience with physical characterization and purification of therapeutic proteins, implementing a broad range of approaches including, but not limited to CD, light scattering, fluorescence spectroscopy, AUC, UV-Vis & IR spectroscopy, SEC, HPLC, AFM, TEM… Developed an instrumental method for determination of tau protein stability using light scattering and fluorescence spectroscopy, resulting in increase of efficiency by 30% compare to previous protocol used, decreasing the time spent in this task and increasing the amount of data produced.
- Independently derived projects from inception to completion; planed & executed goal scientific experiments, prepared technical memos, analytical methods, protocols, SOPs, publications, and oral presentations at internal and external meetings, which helped to develop good writing/oral skills and kept abreast of scientific development in the field.
- Demonstrated in vitro conditions for the first time a novel approach for revealing the molecular mechanism of amyloid polymerization from natively folded protein near physiological conditions.
- Constantly trained and supported other personnel on techniques and equipment while participating in inter-departmental task teams, resulting in 2 successfully accomplished inter- departmental projects, each resulting in a published peer-reviewed article.
- Hands-on experience with physical/mechanical characterization of biological materials/biopolymers, exploring their structure, size, morphology and their aggregation propensities, using a wide range of techniques: DLS, CD, FTIR, fluorescence spectrophotometer, nanoparticle tracking analyses (NTA), AFM, and TEM.
University of South Florida - ,
University of Prishtina - ,
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School Attended
- University of South Florida
- University of Prishtina
Job Titles Held:
- Senior Scientist
- Research Scientist
- Postdoctoral Fellow
- Research Assistant
Degrees
- Ph.D
- B.Sc
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