Scientist resume example with 10+ years of experience
JessicaClaire
Montgomery Street, San Francisco, CA94105609 Johnson Ave., 49204, Tulsa, OK
Home: (555) 432-1000
Cell:
resumesample@example.com
Summary
A researcher with a broad range of scientific experience in academic and industry settings in the fields of molecular and cellular biology, biochemistry, microfluidics. Self-motivated problem solver who is fearless in taking a cross-disciplinary, collaborative approach to delivering solutions. Experienced in various biochemistry techniques (protein and nucleic acid analysis) and spectroscopy techniques. Highly effective writer and oral communicator who excels in presenting scientific information. A fast learner and adaptor to new skills.
Experience
Scientist, 08/2016 to Current Principia Biopharma Inc. – Northborough, MA,
Liquid biopsy research and development
Developed and optimized assays for circulating tumor cell isolation on LiquidBiopsy® platform.
Regularly perform molecular analysis on ctcDNA and cfDNA using next generation sequencing.
Investigated omniphobic surface coating on microfluidic chip to prevent thrombosis.
Provide technical support and arrange technology transfer.
Ph.D. Candidate, 05/2012 to 07/2016 University Of Arkansas – Hope, AR,
Investigations of talin mediated integrin activation using Nanodisc
Investigated the mechanism of the membrane recruitment and auto-inhibition of talin. Identified PIP2 as a key player for talin mediated integrin activation.
Demonstrated a novel conformational change of talin that mediated integrin activation.
Developed a novel Nanodisc FRET binding assay for measuring protein-membrane interactions.
Ph.D. Candidate, 11/2011 to 08/2012 University Of Illinois At Urbana-Champaign – City, STATE,
Biochemical and structural studies of cytochromes P450
Generated the membrane embedded and inactive form of cytochrome P450cam, with high pressure induction for structural study of its hydroxylation chemistry. Identified histidine replacing cysteine as the heme ligand in the P420-CO-bound state. This research is a collaboration with Dr. Paul Champion at Northeastern University.
Revealed the shape and orientation of the membrane embedded Cytochrome P450 3A4 (CYP3A4) in Nanodiscs. This project is a collaboration with Dr. Nicholas Skar-Gislinge at University of Copenhagen.
Undergraduate Research Assistant, 06/2010 to 05/2011 Sun Yat-Sen University – City, STATE,
The Structures of tRNA-binding-protein and Telosome/shelterin Complex
Optimized the expression and purification of protein and nucleic acids of interest, such as the Trm4p protein, ThiI protein, tRNAGly, and tRNASer, for X-Ray Crystallography structural study.
Education and Training
Bachelor of Science: Biotechnology, Expected in 2011 Sun Yat-Sen University - Guangzhou, Guangdong GPA:
School of Life Sciences
GPA: 3.88 out of 4.0
Skills
Biochemistry & Biophysics:
Mass Spec, UV & Fluorescence Spectroscopy, HPLC & FPLC, Protein interaction assay, Nanodiscs technology, Protein purification, Protein modification and conjugation, Bacterial culture, Cell culture, Cell imaging;
Molecular Biology:
Next generation sequencing, ctcDNA and cfDNA purification, Site-directed Mutagenesis, DNA Cloning, Primer design, PCR;Bacterial culture, Cell culture, Cell imaging;
Computer:
Matlab, Origins, VMD, Serial Cloner, Photoshop, Microsoft office, Latex.
Activities and Honors
2011-2016 Guangzhou Elite Graduate Fellowships
2016 Biochemistry Graduate Travel Grant
2016 Cell & Molecular Biology Travel Award
2016 Biochemistry Graduate Student Travel Grants
2014 Robert L. Switzer Award for Teaching
2010 Best student leader of 16th Guangzhou Asian Game
2010 Outstanding Volunteer of 16th Guangzhou Asian Game
2009-2010 Second Prize Merit Scholarships for Excellent Student in SYSU (top 3 of class)
2008-2009 Tianpu Scholarships for Excellent Student of SYSU (top 3 of class)
2007-2008 First Prize Merit Scholarships for Excellent Student in SYSU (top 3 of class)
2007 World International Property Organization Outstanding Innovation Award (One of the only three prizes of the conference)
Languages
English: Professional Proficient.
Mandarin: Native Language.
Cantonese: Native Language.
Publications
1. Ye X, Mclean M, Sligar SG. The Conformational Equilibrium of Talin is regulated by Anionic Lipids. BBA Biomembranes, 2016.
2. Ye X, Mclean M, Sligar SG. PIP2 Modulates the Affinity for Talin-1 to Phospholipid Bilayers and Activates its Auto Inhibited Form. Biocheimstry, 2016.
3. Skar-Gislinge N, Kynde S, Denisov I, Ye X, Lenov I, Sligar SG, Arleth L. Small-angle scattering determination of the shape and orientation of human cytochrome P450 embedded in a phospholipid nanodisc environment (Cover paper). Acta Crystallographica Section D, 2015.
4. Sun Y, Zeng W, Benabbas A, Ye X, Denisov I, Sligar SG, Du J, Dawson JH, Champion PM. Investigations of heme ligation and ligand switching in cytochromes p450 and p420. Biochemistry, 2013.
SELECTED AWARDS & HONORS
2011-2016 Guangzhou Elite Graduate Fellowships
2016 Biochemistry Graduate Travel Grant
2016 Cell & Molecular Biology Travel Award
2016 Biochemistry Graduate Student Travel Grants
2014 Robert L. Switzer Award for Teaching
2010 Best student leader of 16th Guangzhou Asian Game
2010 Outstanding Volunteer of 16th Guangzhou Asian Game
2009-2010 Second Prize Merit Scholarships for Excellent Student in SYSU (top 3 of class)
2008-2009 Tianpu Scholarships for Excellent Student of SYSU (top 3 of class)
2007-2008 First Prize Merit Scholarships for Excellent Student in SYSU (top 3 of class)
2007 World International Property Organization Outstanding Innovation Award
(One of the only three prizes of the conference)
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