Life Scientist with a Ph.D. in Biochemistry & Molecular Biology. Well organized, team-oriented, dedicated worker with an enthusiastic approach to challenges of research and with strong communication skills. Extensive experience with current methods of cell biology, biochemistry and immunology. Able to envision new interpretations of experimental findings. Experienced in research, product development and project management. Expertise in Research Experienced in cell biology: cultured adherent cells: endothelial (HUVEC), epithelial (ARPE-19, MDCK, Caco2), fibroblasts (NIH3T3) and neuroblastoma (N2a) cells; cultured muscle myoblasts C2C12 (myocytes) and performed their differentiation into myotubes; cells in suspension: leukemia K-562; preserved stocks; performed very efficient cell transfection; organized inventories. Studied cell receptors (PDGFR, FGFR, EGFR, TGFR, TNFR, VEGFR,Toll-like & integrin receptors), and their ligands as well as the mechanisms involved in signal transduction cascades (second messenger's generation, receptor's clustering, cascades of protein phosphorylation). Signal transduction pathways in physiological conditions and in various diseases (celiac disease, Age Related Macular Degeneration). Developed new as well as adapted and optimized established techniques (Cell based ELISA for CD46, CD55, CD59; Fluorescence based permeability assay for differentiated Caco2 monolayer treated with cytokines; quantitative ELISA assay for prion protein in blood; quantitative assay for fibrinogen degradation products in blood). Investigated RhoA GTPase in its role in cell adhesion, cytoskeleton organization and assembly of actin stress fibers upon integrin receptor's engagement in fibronectin/tissue transglutaminase (extracellular matrix) interaction; suppression of src tyrosine kinase inhibitory effect on RhoGTPase Activating Protein (p Have broad knowledge in biological sciences exercised in numerous projects in both academia and industry, leading to high level of confidence in work Highly adaptable and goal oriented, multitasking work style