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Postdoctoral fellow & Assistant Project Scientist Resume Example

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POSTDOCTORAL FELLOW & ASSISTANT PROJECT SCIENTIST
Professional Summary
Expert in the fields of inflammatory bowel diseases, immunology, cardiovascular diseases, myocardial infarction, epigenetics, and stem cell biology. Proficient in molecular and cellular biology with extensive knowledge in aseptic cell culture, immunophenotyping, and in vivo disease models. Strong project management, supervisor, teaching, communication, and interpersonal skills. Highly motivated in contributing, evolving, and leading as a scientist in an innovative and productive environment, towards discovery of novel targets, and efficacious new therapeutics.
Areas of Expertise
Single and multiplex ELISA, MACS cell isolation, multicolor FACS analysis and sorting, CFSE assays. Histological analysis: Routine processing of human intestinal biopsies, confocal microscopy, immunofluorescence, immunohistochemistry, dissection of mice. Bioinformatics/Software: Ingenuity (IPA), nSolver, microRNA-binding prediction algorithms, Prism 6, Hierarchical Clustering Explorer, Image J, FACSDiva, FlowJo, Adobe Illustrator, Zeiss Zen. Instruments/Automation: Nanostring nCounter, xCELLigence RTCA, BD Accuri C6/LSRFortessa/FACSAria, Bio-Plex 3D suspension array system, Zeiss confocal.
Work Experience
Postdoctoral fellow & Assistant Project Scientist
January 2012 to Current
Company Name - City, State
  • Permanent resident ("Green Card" holder) through National Interest Waiver (NIW) visa as an outstanding scientist.
January 2005 to January 2012
  • Discovered the anti-growth role of Wnt signaling on cardiac stem cells and myocytes following heart failure models.
  • Identified ABCG2 as key regulator of cardiac stem cell proliferation and asymmetric division.
  • Performed the first direct comparison of the molecular profiling of various mouse cardiac stem cell populations.
  • Discovered the cardio-protective role of Flt3 signaling following myocardial infarction.
January 2004 to January 2005Company Name
  • Revealed the contribution of bone marrow cells in cardiac regeneration following myocardial infarction.
  • Head of the IBD Laboratory at UCLA.
  • Responsible for developing/coordination of 5 new projects and 8 collaborations within academia and industry (Genentech, Gilead, Takeda).
  • Mentored/trained 3 students and 2 fellows.
  • Scientific supervisor of the IBD Biobank at UCLA (>5,000 bio-materials, 12 projects and 5 publications).
  • Established and managed UCLA IBD Biobank.
  • Responsible for training, coordination and evaluation of personnel, database maintenance, administrative duties, bio-sample collection, processing, distribution, quality control.
Education
PhD : 2011University of Crete, School of MedicineGreeceCellular and Genetic Etiology, Diagnosis and Treatment of Human Disease
MSc : Molecular Medicine, 2006University of Crete, School of Medicine, Greece. Research performed in Boston UniversityMolecular Medicine
BS : Biology, 2004University of CreteGreeceBiology
Publications
Circulation, AJP-Heart and Circulatory Physiology (AJP-Heart) and Gastrointestinal and Liver Physiology (AJP-GI). PUBLICATIONS (from a total of 17) Oikonomopoulos A.#, van Deen KW., Manansala A., Lacey NP., Tomakili AT., Ziman A., Hommes DW. "Optimization of human mesenchymal stem cell manufacturing: the effects of animal/xeno-free media". Nature Scientific Reports, 2015 5; 16570. #Corresponding author. Polytarchou C.*, Oikonomopoulos A.*, Joshi S., Touroutoglou A., Koukos G., Hommes WD., Iliopoulos D. "Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology.". Inflam Bowel Dis. 2015; 21(11):2533-9. * Equal contribution. Polytarchou C., Hommes D.W.*, Palumbo T.*, Hatziapostolou M.*, Koutsioumpa M., Koukos G., van der Meulen-de Jong AE., Oikonomopoulos A., van Deen WK., Vorvis C., Serebrennikova B.O., Birli E., Choi J., Chang L., Anton PA., Tsichlis NP., Pothoulakis C., Verspaget HW., Iliopoulos D. "Therapeutically targeting miR-214 circuit in ulcerative colitis and colitis-associated colon cancer". Gastroenterology. 2015; 149(4):981-992. Koukos G., Polytarchou C., Kaplan JL., Oikonomopoulos A., Ziring D., Hommes D., Wahed R., Kokkotou E., Pothoulakis C., Winter HS., Iliopoulos D. "A MicroRNA Signature in Pediatric Ulcerative Colitis: Deregulation of the miR-4284/CXCL5 pathway in the Intestinal Epithelium". Inflam Bowel Dis. 2015; 21(5):996-1005. Law I.K., Bakirtzi K., Polytarchou C., Oikonomopoulos A., Hommes W.D., Iliopoulos D., Pothoulakis C. "Neurotensin-regulated miR-133* is involved in proinflammatory signaling in human colonic epithelial cells and in experimental colitis.", Gut. 2015; 64(7):1095-104. Oikonomopoulos A., van Deen W.K., Hommes D.W. Anti-TNF antibodies in Inflammatory Bowel Disease: do we finally know how it works? Curr Drug Targets. 2013; 14(12):1421-32. Pfister O., Lorenz V., Oikonomopoulos A., Xu L., Häuselmann SP., Mbah C., Kaufmann AB., Liao R., Wodnar-Filipowicz A., Kuster MG. "Flt3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes." Journal of American College of Cardiology (JACC). 2013; 19. Vol 63 (10). van Deen W.K., Oikonomopoulos A., Hommes D.W. Stem cell therapy in inflammatory bowel disease: which, when and how? Curr Opin Gastroenterol. 2013; 29(4):384-90. Dey D., Han L., Bauer M., Sanada F., Oikonomopoulos A., Hosoda T., Unno K., De Almeida P., Leri A., Wu JC. "Dissecting the molecular relationship among various cardiogenic progenitor cells." Circ Res. 2013; 112(9):1253-62. Sereti K.-I., Oikonomopoulos A., Unno K., Cao X., Qiu Y., Liao R. "ATP-binding cassette G-subfamily transporter 2 regulates cell cycle progression and asymmetric division in mouse cardiac side population progenitor cells." Circ Res. 2013; 112(1):27-34. Oikonomopoulos A., Sereti K.-I., Conyers F., Bauer M., Liao A., Guan J., Crapps D., Han JK., Dong H., Bayomy A.F., Fine GC., Westerman K., Biechele TL., Moon RT., Force T., Liao R. "Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3". Circ Res. 2011; 109(12):1363-74. Oikonomopoulos A., Sereti K.-I., Liao R. "Resident cardiac stem/progenitor cells for cardiac regeneration". Drug Discovery Today: Therapeutic Strategies, 2008; 5 (4), 193-199. Pfister O.*, Oikonomopoulos A.*, Sereti K.-I.*, Sohn RL., Cullen D., Fine GC., Mouquet F., Westerman K., Liao R. "Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells". Circ Res. 2008; 103:825-35. * Equal contribution. Mouquet F., Pfister O., Jain M., Oikonomopoulos A., Ngoy S., Summer R., Fine A., Liao R. "Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells". Circ Res. 2005; 97:1080-2. MANUSCRIPTS IN PREPARATION Oikonomopoulos A.*, Polytarchou C.*, Joshi S., Hommes DW., Iliopoulos D. "Circulating microRNAs as biomarkers for the diagnosis and disease activity evaluation in Crohn's Disease patients".*Equal contribution. Oikonomopoulos A., Polytarchou C., Lacey N.P., Tomakili A.T., Hatziapostolou M., Iliopoulos D., Hommes W.D. "MicroRNA-29a/b regulates the immunosuppressive properties of human bone marrow MSC". LECTURES AND PRESENTATIONS (from a total of 11) Novel Insights on IFN-* primed MSC" 12th Annual Broad Medical Research Program Investigator Meeting, Los Angeles, USA, 4/11/2014. Stem Cell Therapy in IBD" Educational course 'Caring for your Crohn's Disease and Ulcerative Colitis Patient', UCLA Center for IBD. University of California, Los Angeles, USA, 10/6/2013. Role of Wnt signaling in regulating the function of adult cardiac progenitor cells". Brigham and Women's Hospital, Biomedical Research Institute. Work in progress research seminar- division of cardiology. Boston, USA, 1/26/2011. Role of Wnt signaling in the cell fate of cardiac progenitor cells" Research seminar between the Cardiology divisions of Brigham and Women's Hospital, and Beth Israel Hospital. Boston, USA, 1/15/2010. The role of Wnt signaling in cardiac side population cells". Summer retreat organized by the laboratories of Dr. Loscalzo J (Chairman, Department of Medicine, Harvard Medical School) and Dr. Ronglih Liao at Boston, USA, 02/08/2008.
Skills
3D, administrative duties, Adobe Illustrator, Automation, biology, cancer, Clustering, database, Diagnosis, DNA, ELISA, Harvard, Image, imaging, Explorer, MACS, materials, PCR, personnel, PhD, Prism 6, coding, publications, quality control, reporter, Research, sample collection, Scientific, sorting, supervisor
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Resume Overview

School Attended

  • University of Crete, School of Medicine
  • University of Crete, School of Medicine, Greece. Research performed in Boston University
  • University of Crete

Job Titles Held:

  • Postdoctoral fellow & Assistant Project Scientist

Degrees

  • PhD : 2011
    MSc : Molecular Medicine , 2006
    BS : Biology , 2004

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