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Postdoctoral Fellow Advisor Resume Example

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POSTDOCTORAL FELLOW ADVISOR
Professional Summary
Goal-driven research scientist in the field of molecular and cellular biology. * Passionate and collaborative scientist with proven record of project design and execution. * Team-oriented mentor with strong communication and organizational skills. * Good understanding and proficient hands-on techniques in molecular and cellular biological research and in vitro/cell based assay system development. Molecular Biology Molecular cloning, in vitro mRNA synthesis, Real-time PCR (qPCR), Western blotting Cell Biology Rodent primary neuron culture, Mammalian cell culture, Stable cell line construction, transfection/infection, Gene knockdown/knockout by shRNA system, Fluorescent microscopy Biochemistry Enzyme assays, DNA/RNA gel electrophoresis, Luciferase reporter assays, ELISA, Immunoprecipitation Protein Characterization Protein expression/purification from mammalian cell line, Protein expression/purification from bacteria/yeast/insect cell, FPLC chromatography
Work History
Department of Life Sciences
Accomplishments
  • 1) Shin J.
  • Paek KY.
  • Ivshina M, Stackpole EE, and Richter JD Essential role for no-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism Nucleic Acids Res.
  • 2017; 45(11):6793-6804 (.
  • equal contribution).
  • 2) Jang SK and Paek KY Cap-dependent translation is mediated by 'RNA looping' rather than 'ribosome scanning'.
  • Review paper) RNA Biol.
  • 2016; 13(1):1-5.
  • 3) Paek KY, Hong KY, Ryu I, Park SM, Keum SJ, Kwon OS, Jang SK.
  • Translation initiation Mediated by RNA looping.
  • Proc Natl Acad Sci USA 2015 Jan 27;112(4):1041-6.
  • 3) Lee SH, Oh J, Park J, Paek KY, Rho S, Jang SK, Lee JB.
  • Poly(A) RNA and Paip2 act as allosteric regulators of polyA()-binding protein.
  • Nucleic Acids Res.
  • 2014 Feb;42(4):2697-707.
  • 4) Paek KY, Park SM, Hong KY, Jang SK.
  • Cap-dependent translation without base-by-base scanning of an mRNA.
  • Nucleic Acids Res.
  • 2012 Aug;40(15):7541-51.
  • 5) Park SM, Paek KY, Hong KY, Jang CJ, Cho S, Park JH, Kim JH, Jan E, Jang SK.
  • Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1.
  • Nucleic Acids Res.
  • 2011 Sep;39(17):7791-802.
  • 6) Paek KY, Kim CS, Park SM, Kim JH, Jang SK.
  • RNA-binding protein hnRNP D modulates internal ribosome entry site-dependent translation of hepatitis C virus RNA.
  • J.
  • Virol.
  • 2008 Dec;82(24):12082-93 7) Kim JH, Paek KY, Ha SH, Cho S, Choi K, Kim CS, Ryu SH, Jang SK.
  • A cellular RNA-binding protein enhances internal ribosomal entry site-dependent translation through an interaction downstream of the hepatitis C virus polyprotein initiation codon.
  • Mol Cell Biol.
  • 2004 Sep;24 1) CSHL meeting on Translational Control, 2014, Cold Spring Harbor, NY USA 2) EMBO Conference on Protein Synthesis and Translation Control, 2011, Heidelberg, Germany 3) EMBO Conference on Protein Synthesis and Translation Control, 2011, Heidelberg, Germany 4) CSHL meeting on Translational Control, 2010, Cold Spring Harbor, NY USA 5) EMBO Conference on Protein Synthesis and Translation Control, 2007, Heidelberg, Germany.
Experience
Postdoctoral Fellow Advisor Jan 2013 to Current
 University of Massachusetts Medical School
  • Program in Molecular Medicine, Worcester, MA.
  • Delineated a novel post-transcriptional regulatory network involving carbohydrate metabolism and glucose homeostasis in glioblastoma cells.
  • Identified genome-wide molecular targets of RNA-binding proteins by RNA-seq analysis in rat primary neurons.
  • Mentored multiple graduate/medical student for scientific projects.
Postdoctoral Fellow Advisor Jan 2012 to Jan 2013
 Dr. Mary Munson University of Massachusetts Medical School － Worcester, MA
  • Developed the yeast screening system to identify proteins involved in mRNA export.
Postdoctoral Fellow Advisor Jan 2009 to Jan 2012
 Pohang University of Science and Technology
Jan 2001 to Jan 2009
 Pohang University of Science and Technology － Pohang, South Korea
  • Pohang, South Korea.
  • Formulated a new mechanism of translation initiation.
  • Developed several sophisticated in vitro/in vivo translation assay systems.
  • Led a collaboration with interdisciplinary scientists to demonstrate the new mechanism.
  • Mentored multiple graduate/undergraduate student for scientific projects.
  • Graduate researcher (Advisor: Dr.
  • Sung Key Jang Investigated cellular factors important for Hepatitis C Virus (HCV) proliferation - Generated HCV replication- or infection-competent hepatocellular carcinoma cell lines.
  • Identified and characterized RNA-binding proteins as a positive regulator of HCV translation.
  • Elucidated the molecular mechanism of RNA-binding proteins on HCV translation initiation.
  • Developed luminescence-based assay system to screen small molecule inhibitors against HCV.
Education
Ph.D, Molecular Virology 2009 Pohang University of Science and Technology － Pohang, South Korea Molecular Virology (Advisor: Dr. Sung Key Jang)
B.S, Biology 2000 Yonsei University － Seoul, South Korea Biology
Ph.D 2015 University of Massachusetts Medical School － Worcester, MA Directly mentored MD/ . students in Richter laboratory. Gave technical assistance, guided experimental design, assisted with data interpretation and problem solving.
Directly mentored multiple graduate and undergraduate students in Jang laboratory. Gave technical assistance, guided experimental design, assisted with data interpretation and problem solving. Teaching Assistant 2005 Pohang University of Science and Technology － Pohang, South Korea Pohang, South Korea 2001, 2002 Assisted undergraduate students with laboratory experiments and interpretation of result during weekly Molecular Biology Laboratory sessions. AWARD AND FELLOWSHIP BK21 Postdoctoral fellowship
Publications
(18):7878-90. 8) Choi K, Kim JH, Li X, Paek KY, Ha SH, Ryu SH, Wimmer E, Jang SK. Identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotides. Nucleic Acids Res. 2004 Feb 23;32(4):1308-17. 9) Kim JH, Paek KY, Choi K, Kim TD, Hahm B, Kim KT, Jang SK. Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc mRNA in a cell cycle phase-dependent manner. Mol Cell Biol. 2003 Jan;23(2):708-20.
Skills
C, experimental design, experiments, interpretation, MA, Molecular Biology, network, novel, problem solving, researcher, scientific, Teaching, technical assistance, translation
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Resume Overview

Companies Worked For:

  • Department of Life Sciences
  • University of Massachusetts Medical School
  • Dr. Mary Munson University of Massachusetts Medical School
  • Pohang University of Science and Technology

School Attended

  • Pohang University of Science and Technology
  • Yonsei University
  • University of Massachusetts Medical School

Job Titles Held:

  • Postdoctoral Fellow Advisor

Degrees

  • Ph.D , Molecular Virology 2009
    B.S , Biology 2000
    Ph.D 2015
    Directly mentored multiple graduate and undergraduate students in Jang laboratory. Gave technical assistance, guided experimental design, assisted with data interpretation and problem solving. Teaching Assistant 2005

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