Team oriented, results driven, scientist with a broad range of expertise and 5 years of experience communication
January 2010 to January 2015Memorial Sloan Kettering Cancer Center
000 of private and public funding.
I have co-authored book chapters, written manuscripts and presented at scientific meetings (invited oral, poster, over 30 abstracts).
Advised and assisted clinicians and scientists in their grant and research applications, supervised and trained X# of students, technicians and medical residents and taught undergraduate biology classes.
Initiated X# of interdisciplinary and translational collaborations with academic leaders and clinicians within and across institutes to achieve objectives of the project within a stipulated time frame.
Managed and designed complex experimental procedures, marketed projects to potential collaborators and worked in a fast paced, results driven environment.
Worked as a researcher on phase 0/I clinical trials and well versed with regulatory procedures and requirements.
NY, Department of Molecular Pharmacology and Medicine Wrote X# of grants and awarded private and public funded to the tune of $200,000 and presented scientific findings at X# of national and institutional meetings.
Wrote manuscripts and prepared print quality scientific figures and cartoons to explain scientific content.
Advised and assisted clinicians and scientists in their grant applications, supervised and trained students and technicians.
Developed a potential valuable diagnostic assay that will overcome the current lack of therapeutic focusing and allow appropriate patient selection on Hsp90 clinical trials.
Collaborated with clinicians and KOL's in the field to obtain patient samples and pipeline this project of substantial clinical relevance into a potentially valuable diagnostic tool for the selection of Hsp90 responsive tumors.
Worked as a scientist on Phase 0/I clinical trials and well versed with regulatory procedures and requirements.
January 2006 to January 2010Roger Williams Medical Center/Boston University School of Medicine - RI
Trained and supervised X# of research technicians and clinical residents.
Worked with physicians and senior research scientists to assess patient's samples on phase I clinical trials and analyze clinical data.
Established in vitro and in vivo proof of concept and biomarker markers of in vivo engraftment.
Wrote manuscripts and prepared figures/tables for manuscripts, clinical reports and grants.
Team was awarded $5M department of defense (DOD) grant.
January 2000 to January 2006Baylor University Medical Center/ Baylor University TX, Sammons Cancer Center
Wrote manuscripts, scientific proposals and Laboratory standard operating procedures.
Constantly prepared scientific content in the form of figures, tables, graphs for presentations, grant applications and scientific communications with collaborators in the USA and internationally.
Teaching assistant for Undergraduate Introduction to Biology laboratory course- 4 semesters/60 students/3 sections.
Course entailed illustrating modern concepts of biological sciences, with emphasis on morphology, general physiology, and ecology.
Other duties entailed Organizing class material, laboratory set up, performing and teaching laboratory experiments.
Critically reviewed and graded exams and laboratory reports.
Responsible for inputting and managing student grades.
Promoted active learning: Held discussions and organized review sessions.
Supervised and trained graduate and summer students.
Marketing and Sales Representative January 1999 to January 2000Microlabs - Mumbai, India
Provided technical and promotional information to physicians and retail pharmacists.
Wrote reports on feedback obtained from physicians and retails pharmacists and prepared expense and sales reports.
Ph.D : Biomedical Studies, 2010Baylor University - TXPost-Doctoral Fellow Memorial Sloan Kettering Cancer Center, NY 2010-2015
Post-Doctoral Fellow Roger Williams Medical Center, RI Biomedical Studies
Top 8 out of 43) Zong H, Gozman A, Caldas-Lopes E, Taldone T, Sturgill E, Brennan S, Ochiana SO, Gomes-DaGama EM, Sen S, Rodina A, Koren J 3rd, Becker MW, Rudin CM, Melnick A, Levine RL, Roboz GJ, Nimer SD, Chiosis G, Guzman ML. A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species. Cell Rep. 2015 Dec 15;13(10):2159-73. PMID 26628369 Ma Q, Gomes EM, Lo AS, Junghans RP. Advanced generation anti-prostate specific membrane antigen designer T Cells for prostate cancer immunotherapy. Prostate. 2014 Feb;74(3):286-96.PMID:24174378 Erica M. Gomes DaGama, Kamalika Moulick, James H. Ahn, Hongliang Zong, Anna Rodina, Leandro Cerchietti, Eloisi Caldas-Lopes, Kristin Beebe, Fabiana Perna, Katerina Hatzi, Ly P. Vu, Xinyang Zhao, Danuta Zatorska, Tony Taldone, Peter Smith-Jones, Mary Alpaugh, Steven S. Gross, Nagavarakishore Pillarsetty, Thomas Ku, Jason S. Lewis, Steven M. Larson, Ross Levine, Hediye Erdjument-Bromage, Monica L. Guzman, Stephen D. Nimer, Ari Melnick, Len Neckers, Gabriela Chiosis Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. AACR, 2012, Chicago, IL Taldone T, Gomes-DaGama EM, Zong H, Sen S, Alpaugh ML, Zatorska D, Alonso-Sabadell R, Guzman ML, Chiosis G. Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5347-52. Epub 2011 Jul 14. PMID: 21802945 Gomes EM, Rodrigues MS, Phadke AP, Butcher LD, Starling C, Chen S, Chang D, Hernandez-Alcoceba R, Newman JT, Stone MJ, Tong AW. Anti-tumor Activity of an Oncolytic Adenoviral-CD40 ligand (CD154) Transgene Construct in Human Breast Cancer Cells. Clin Cancer Res. 2009; Feb 15; 15(4): 1317-1325. PMID:19228733 Gomes EM, Ma Q, Junghans RP. Anti-CEA Third Generation Immunologlobulin Chimeric T Cell Receptor Molecules for Adoptive Cancer Immunotherapy. AACR Meeting , Apr 2008, Abstract No. 4625 Gomes EM, Rodrigues MS, Alcoceba Hernandez R, Kansopon J, Newman J, Stone M.J, Tong AW. Enhanced anti-tumor growth inhibition by a conditional-replicative adenovirus armed with the CD154 (CD40L) transgene in human breast cancer cells. AACR Meeting Abstracts, Apr 2006; 2006: 512 Gomes EM, Rodrigues MS, Alcoceba Hernandez R, Kansopon J, Newman J, Stone MJ. Tong A.W. Conditional-replicative adenovirus armed with the CD154 (CD40L) displayed enhanced anti-tumor growth inhibitory properties against human breast cancer cells. Proc.13thAnnual Conference on the Gene Therapy of Cancer, San Diego, CA. 2005. (Abstract invited for oral presentation)
AWARDS Cold spring harbor Laboratory pancreatic cancer travel award 2013 Baylor University graduate student travel award 2006 Baylor University inter-disciplinary award for graduate studies 2006 Goa University honors award for M.Sc. program (graduated with highest distinction) 1999 Undergraduate merit for first class academic achievement 1997
PATENTS Uses of labelled Hsp90 Inhibitors. (WO2013009657), PCT/US2012/045864. Chiosis Gabriela, Taldone Tony, Alpaugh Mary L., Gomes-DaGama Erica M., Guzman Monica L., Hongliang Zong Uses of labelled Hsp90 Inhibitors. (WO2013009655), PCT/US2012/045864. Chiosis Gabriela, Pillarsetty Nagavarakishore, Lewis Jason S., Larson Steven M., Taldone Tony, Alpaugh Mary L., Gomes-DaGama Erica M RESEARCH SUPPORT Weill Cornell Clinical and Translational Science Center Pilot Award 08/11/14- 5/31/16 Total Cost: $50,000/year Development and Validation of Chemical Probes to Identify Oncogenic Hsp90 as a Biomarker for Hsp90 Therapy in Cancer Role: PI David Rubenstein Center for Pancreatic Cancer 1/1/2015-12/31/2015 Total Cost: $100,000 Translation of Hsp90 targeting approaches to the treatment of Pancreatic Cancer Role: Investigator