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computational biologist resume example with 13+ years of experience

Jessica
Claire
resumesample@example.com
(555) 432-1000,
, , 100 Montgomery St. 10th Floor
:
Summary

An experienced computational Biologist with 10 years of leadership experience managing research projects, data analysis, and Interpretation in the field of genomics and bioinformatics. Offering articulate technical writing skills to prepare technical documents, manuscripts, and SOPs. Adept in using Computational genomics, genetics, and bioinformatics to analyze complex data with strong problem-solver, excellent communication, multitasking, and organizational abilities paired with diverse biological training and an accuracy-driven approach.

Skills
  • Programming Skills: R (Advance), Python (Advanced), shell/bash scripting (Advanced)
  • Biostatistics: R, Python, Excel, SAS, JMP
  • OS platform: Linux, MacOS, Window OS, Cluster distributed computing (HPCC)
  • Bioinformatics Skills and Expertise
  • Genomics: NGS data analysis (bulk seq, sRNAs), Single-cell omics and integration, pathways enrichment and ontology analysis, network analysis, and (BWA-mem, Bowtie, MiniMap2, RepeatMasker, HMM, Kallisto, SAMtools, BAMTools, Deseq2, GATK, BEDtool, Maker, Blast2GO etc)
  • Modeling & Statistics: Feature selection, ML/DL Model building and optimization, regression and classification model. (R, regression, bayesian, SAS, JMP, Excel etc.)
  • Structural Biophysics: Protein and Nucleic Acid homology Modeling, Pairwise comparison, Evolutionary distance, Pearson correlation analysis, Free Energy Calculations, Kinetic dynamics
  • Basic Bioinformatics and system biology: Sequence analysis, HPC distributed computing, etc. (Linux, MacOS, ROCKS, sun-grid, Linux, etc)
  • Specimen Collection
  • Research Management
Education and Training
Michigan State University East Lansing, Expected in 12/2020 Ph.D. : Plant Breeding, Genetics, And Biotechnology - GPA :

THESIS: The Consequences of Gene Duplication by DNA Transposons and Their Interaction with Host Genomes and Retrotransposons

Purdue University West Lafayette, IN, Expected in 05/2008 Bachelor of Science : Biological Sciences - GPA :
  • Dean's List Spring 2005
Experience
Applied Materials - Computational Biologist
Washington, DC, 03/2021 - Current
  • Development of genomic models of transposition using Nanopore long read sequencing, Analysis, integration, and interpretation of transpon types to quantify different insertion rates and dynamics.
  • Created CRISPR knockout of p53 in fruit fly (Drosophila virilis) to analyze how genome response to DNA double-strand breaks vary in different genetic backgrounds.
  • Analyze piRNA levels in genomes to compare variance in different species, genetic backgrounds, and experiments.
  • Used computational tools to create unique databases of transposable elements in different genomes.
  • Modified existing software pipeline to enhance performance and add new features.
  • Communicated research results through conference presentations, scientific publications, and project reports.
Ecolab Inc. - PhD Graduate
Columbia, SC, 08/2011 - 12/2020
  • Analyzed whole genome interactions of genes and transposons in Sacred lotus (Nelumbo nucifera).
  • Compared intron size across plants showing wide variation caused by transposon insertions.
  • Genomics (bulk-seq, and methylation) of drought tolerant plant to analyze interactions of multiple transposon families
  • Developed PCR screening method for observing sequence specific gene acquisition.
  • Discovered amplification of copy number due to an evolutionary adaptation of regulatory Ago1 gene in species of the tomato clade
  • Supported department faculty with faculty hiring committee positions (2), served as treasurer of the graduate student group, and student government representative.
  • Educated undergraduate and high school students on laboratory protocols and activities.
  • Served as mentor to other graduate students.
DSM Food Specialties - Quality Analyst
City, STATE, 01/2009 - 08/2012
  • Developed and maintained quality assurance procedure documentation.
  • Collaborated with management to provide training on improved processes and assisted with creation and maintenance of quality training.
  • Developed training materials, SOPs, and work instructions to supplement new team member onboarding.
  • Analyzed global assay variance by analyst using JMP and rewrote SOPs and/or trained individuals to improve outcomes.
  • Defined and implemented quality initiatives to reduce risk by adding testing standards which increased assay qualification by 25%.
  • Administered 8 internal quality and safety audits, and assessed results to inform corrective action measures.
  • Monitored KPIs to proactively address bottlenecks and quality issues.
Additional Information

1. Jessica Claire and Justin Blumenstiel, “MARvirilis: A Tc1/Mariner element in Drosophila virilis shows evidence of horizontal transfer in drosophila,” in prep.

2. Danny E. Miller, Ana P. Dorador, Kelley Van Vaerenberghe, Angela Li, Emily K. Grantham, Jessica Claire, Celeste Cummings, Marilyn Barragan, Rhonda R. Egidy,

Allison R. Scott, Kate E. Hall, Anoja Perera, William D. Gilliland, R. Scott Hawley, and Justin P. Blumenstiel, “Off-target piRNA gene silencing in Drosophila melanogaster rescued by a transposable element insertion,” Plos Genetics, in press, 2023.

3. Ana P Dorador, Martina Dalikova, Jessica Claire, Chris M Stillman, Molly G Zych, R Scott Hawley, Danny E Miller, David A Ray, Sergei Y Funikov, Michael B Evgen’ev, Justin P Blumenstiel, “Paramutation-like Epigenetic Conversion by piRNA at the Telomere of Drosophila virilis,” Biology, volume 11, Number 10, 1480, 2022. DOI: 10.3390/biology11101480

4. Jessica Claire, Shujun Ou, Yang Li, Yanni Sun, and Ning Jiang, “Distinct composition and amplification dynamics of transposable elements in sacred lotus (Nelumbo nucifera Gaertn.),” The Plant Journal, Volume 112, Issue 1, 172-192, 2022. DOI: 10.1111/tpj.15938

5. Jessica Claire, Ching Man Wai, Robert VanBuren, and Ning Jiang, “GingerRoot: a novel DNA transposon encoding integrase-related transposase in plants and animals,” Genome Biology and Evolution, Volume 11, Issue 11, 2019, 3181–3193. DOI: 10.1093/gbe/evz230

6. Jessica Claire and Ning Jiang, “Duplication of host genes by transposable elements,” Current Opinion in Genetics & Development Volume 49, 49:63–69, 2018. DOI: 10.1016/j.gde.2018.03.005

7. Ya-Nan Xia, Yaqiong Liu, Haoran Wang, Qing Hu, Jessica Claire, and Jie Wang, “Comparison on Flavor Compounds of Jujube Brandies Brewed from Eleven Varieties,” American Journal of Food Technology, Volume 12, Number 6, 345-357, 2017a.

8. Ya-nan Xia, Ran Suo, Haoran Wang, Jessica Claire, and Jie Wang, “Optimization of the Degree of Toasting, Concentration and Aging Time of Quercus mongolica (Chinese Oak) for Jujube Brandy Aging,” American Journal of Food Technology, Volume 12, Number 5, 311-321, 2017b.

9. Ya-nan Xia, Ran Suo, Haoran Wang, Jessica Claire, and Jie Wang, “Analysis on Flavor Compounds of Jujube Brandy from Different Fermentation Heights by HS-SPME-GC/MS, E-nose and E-tongue,” American Journal of Food Technology, Volume 12, Number 5, 332-344, 2017c.

Accomplishments
  • Dissertation Completion Graduate Fellowship $7000
  • Corteva UIUC Plant Sciences Symposium 1st Place Poster
  • Corteva UIUC Plant Sciences Symposium Travel Grant
  • MSU Graduate Student Summer Critical Needs fellowship $7000
  • Horticulture Office of Graduate Student Travel Grant
  • MSU Sustainability Grant $2900
  • Council of Graduate Students Grant (x3) $1500
  • Association of Students at Michigan State University Grant $5500
  • MSU Plant Science Summer Fellowship $7000
  • Dr. Leo W. Mericle & Dr. Rae Phelps Mericle Memorial Scholarship
  • Graduate Research Support Fellowship $1500


Languages
English :
Native or Bilingual
Negotiated :
French :
Professional Working
Negotiated :

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Resume Overview

School Attended

  • Michigan State University
  • Purdue University

Job Titles Held:

  • Computational Biologist
  • PhD Graduate
  • Quality Analyst

Degrees

  • Ph.D.
  • Bachelor of Science

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