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Research Assistant Resume Example

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RESEARCH ASSISTANT
Career Overview
To obtain a full time position as a Bioinformatician to work on challenging interdisciplinary computational problems where I can extend and enhance my technical expertise while contributing to the success of the company. Informatics student holding experience of 3 years at computational and analytical skills developed over the years in Bioinformatics Proficient in Data Analysis, Data Handling and possess excellent research, communication, analytical, troubleshooting skills and ability to work in a UNIX environment. Well versed with Comparative/Genomic data analysis (NGS and Microarray data) using scripting languages and Bioconductor packages in R. Skilled in managing and handling tasks efficiently in a fast paced and dynamic environment. Developed pipeline for quick and automated Next-generation and High-throughput data. Successfully handled large datasets and extensive literature mining experience.
Qualifications
Python, R, HTML, CSS, PHP, SQL, Perl *Operating system: MS Windows, Unix, Linux, MacOS *Bioformatics applications: Samtools, Bismark, MethylKit, GATK, Bioconductor, BWA, Bowtie, BLAST, MEME, MACS, WEKA, FASTX, Bedtools
Accomplishments
  • Bioinformatics Related Projects Developed of a gene terrain database using data for different types of cancer from databases such as PAGER, HAPPI and TCGA using JAVA, SQL.
  • Web use interface for the database using PHP, HTML, JavaScript.
  • Gene expression analysis for mutant tp53 (cancer datasets) and effect on mevelonate pathway by analyzing microarray datasets using GEOR, calculation of fold change, R Bioconductors for statistical analysis, functional enrichment using DAVID and PANTHER.
  • Developed RNA-Seq pipeline for the functional, pathway and statistical analysis for the differentially expressed genes between the smokers, non-smokers, never smokers and current smokers group using R, Unix, Bowtie, Cuffliks.
  • To understand the pattern of methylation in Glioblastoma Multiforme samples from TCGA.
  • array based data) (Unix, R Bioconductor- DESeq) Developed a Bisulfite Sequencing pipeline for Glioblastoma Multiforme samples from CGHub to understand methylation patterns using Alignmer- BSMap, Analysis- Methylkit (Unix, R, MS Excel) Developed a ChIP-Seq analysis pipeline for peak detection with respect to Mantle Cell Lymphoma samples and comparative analysis of motif searching algorithms DREME, ChipMunk, HOMER, Cis-Finder by evaluating performance and efficiency.
  • Health Informatics Related Projects Research and identification of measures to improve the efficiency of Meaningful Use Stage II and create training documentation and clinical quality measures which help physicians improve quality of patient care through better clinical decision support, patient engagement and care coordination.
  • Analysis of the impact of managed care organizations of the use of technology for Medicaid beneficiaries.
Work Experience
Research Assistant
January 2015 to CurrentIU-School of Medicine, Indianapolis
  • Center for Computational Biology and Bioinformatics Thesis Project: Curation of abstracts related to Clinical Phase-I clinical trials study from PubMed and other sources.
  • Integration of ontology and corpus for Text Mining.
  • Python, NLP tools).
  • Performed Clinical data analysis of over seven thousand records from public database (ClinicalTrials.gov) for study of single and combinational drugs and their side effects for breast cancer.
  • Data extraction and statistical methods using R and Python).
Research Assistant
August 2014 to May 2015School of Informatics and Computing, Indianapolis
  • Performed proteomic data analysis to identify Graft-versus-Host disease biomarkers in leukemia using Trans Proteomic Pipeline (TPP) and related tools.
  • Data analysis- UNIX).
  • Designed user interface for proteomics data and for related pipeline using HTML, CSS, PHP, and JavaScript.
Research Associate
October 2012 to February 2014Eminent Biosciences － Indore, India
  • Screening, isolation and identification of polygalacturonase producing Bacillus tequilensis and probiotic producing lactobacillus acidophilus strains by 16S rRNA gene sequencing.
  • Performed phylogenetic analysis and BLAST Accession Number - KC150145, KC171015- GenBank respectively.
  • Identification and functional annotation of differentially expressed genes of Breast Cancer data by RNA Seq Analysis involving TopHat, Bowtie, Cufflinks and EgdeR packages in R for differential gene expression.
Student Intern
August 2011 to January 2012Eminent Biosciences － Indore, India
  • Hydrophobic patches recognition, protein-protein docking and protein-ligand docking used to investigate better HSP90 inhibition.
  • Structure predictions and modelling of Breast Cancer Resistance Protein (BCRP) and its mutant variants using MODELLER for homology modelling ,Rasmol, PyMOL for visualization and structure validation using algorithm Procheck to study the drug resistance and implications on breast cancer.
Education and Training
MS : May 2016Indiana University Indianapolis
M.Sc Biotechnology : Oct 2012Softvision College, Devi Ahilya Vishvavidhalya － Indore, India
B.Sc Biotechnology : May 2010SJHSSICCS, Devi Ahilya Vishvavidhalya － Indore, India
Publications
In silico investigations on HSP90 and its inhibition for the therapeutic prevention of breast cancer, (Journal of Pharmacy Research. Elsevier. Vol 7 Issue 2 March 2013). *Isolation and screening of Polygalacturonase producing Bacillus tequilensis strain EMBS083, (European Journal of Biological Sciences 5(1): 09-13, 2013). *Screening, Isolation and Identification of Probiotic Producing Lactobacillus acidophilus strains EMBS081 & EMBS082 by 16S rRNA Gene Sequencing (Interdisciplinary Sciences Computational Life sciences, Springer (2014) 6:1-6). *Pharmacogenomics of drug resistance in Breast Cancer Resistance Protein (BCRP) and its mutated variants, (Journal of Pharmacy Research. Elsevier. Vol 6 Issue 7 July 2013).
Skills
Biology, Cancer, clinical trials, CSS, Data analysis, database, functional, HTML, PHP, JavaScript, Linux, MACS, MacOS, MS Windows, NLP, Operating system, Perl, producing, Python, SQL, UNIX, user interface, validation
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Resume Overview

Companies Worked For:

  • IU-School of Medicine, Indianapolis
  • School of Informatics and Computing, Indianapolis
  • Eminent Biosciences

School Attended

  • Indiana University Indianapolis
  • Softvision College, Devi Ahilya Vishvavidhalya
  • SJHSSICCS, Devi Ahilya Vishvavidhalya

Job Titles Held:

  • Research Assistant
  • Research Associate
  • Student Intern

Degrees

  • MS : May 2016
    M.Sc Biotechnology : Oct 2012
    B.Sc Biotechnology : May 2010

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