Research | Chemistry |Biology Premier chemist with 5+ years of experience in materials science and soft matter. Skilled in engineering molecular links at nano-bio interface and in designing analytical sensors for biological and cellular systems. Expert in surface fabrication and bioconjugation techniques for effective targeting, controlled release, and biodistribution of drug formulations. Proven ability in providing analytical solutions and resolving chemical discrepancies within cross-functional research teams. Eloquent in technical writing and oral skills; coauthored >25 publications in peer-reviewed journals and presented invited lectures, oral and poster presentations in various national and international conferences. Laboratory Team Leader Project Management Product Development Particle Formulation Functional Materials Organic Chemistry Polymers Nanotechnology Biochemical Sensors Nucleic acid Bioanalytical Assays Research Chemist offering expertise in GLP laboratory requirements and procedures. Skillfully uses standardized chemical extraction methods and analytical results documentation for final study records. Analytical Research Chemist with exceptional problem solving and operational skills desires a position at a [Lab type] lab.
High-Performance Liquid Chromatography
Specialization in colloid chemistry
Trained in lab safety
Postdoctoral Fellow, 09/2012 to 08/2014 University of North Carolina, Eshelman School of Pharmacy – NC
Managed and designed biomarker discovery project based on nanoparticle technology.
Developed a cost-effective protocol for bulk production of composite nanomaterials and significantly reducing production cost, processing steps and usage of toxic chemicals.
Evaluated effects of polymer (PEG) size and conformation on PEG antibody binding patterns for improved targeting and prolonged drug retention times.
Observant to project shortcomings and efficiently troubleshoot with available resources and better cost effective alternatives.
Organized special brainstorming sessions for juniors and staff technicians to promote out-of-the box thinking and adopt innovative and critical research approach.
Maintained laboratory instruments and developed new laboratory equipment.
Organized lab test solutions, compounds and reagents.
Interpreted test results and developed nonstandard tests.
Accurately inventoried lab chemicals and supplies.
Developed products and technologies that met product performance, quality and timing requirements.
Operated and maintained analytical instruments such as FTIR, GC and Calorimeter.
Transitional Postdoctoral Trainee, 08/2011 to 08/2012 MD Anderson – FL
Standardized combinatorial treatment involving experimental therapeutics and targeted radiation for ovarian, breast and prostate cancers.
Investigated the direct and long term effects of small molecule drugs on the expression of transcription factors and their role in cancer progression using standard biochemical techniques; Antibody binding assays, protein expression and isolation, mitochondrial activity, ATP, and caspase activity.
Investigated the effect of chemodrugs on cytochrome isozymes and their subsequent role in bioactivation of carcinogens involving esophageal tumorigenesis in rats.
Successful and on-time completion of a chemoprevention project (2 publications and 1 review) by managing and assigning individual tasks to an interdisciplinary research team.
Interpreted research findings and summarized data into reports.
Managed overall laboratory functions.
Scheduled and trained technical staff members.
Designed and optimized assays.
Collected and processed specimens for clinical protocols.
Adjunct Postdoctoral Fellow Group Leader, 08/2009 to 08/2011 University of Florida's Centre for – FL
Formulated aptamer functionalized drug loaded SPIONs for targeted sustained drug release and MRI of tumors.
Demonstrated enhanced cellular uptake of engineered materials and achieved subsequent mapping of immune and biochemical pathways using immunochemistry, cell viability assays, ELISA, westerns blots and electrophoresis.
Devised and developed DNA-based bioanalytical sensors for quantifying trace metabolites in cancer cells and biological fluids with high LOD values.
Trained an 8-membered research team develop reusable and inexpensive sensors for molecular diagnostic tests; DNA-nanoparticle based magnetic relaxation switches for cancer cell profiling.
Logic-based colorimetric sensors for detection of cancer biomarkers in serum or blood samples.
Ph.D: Chemistry, 11 2008 Johannes Gutenberg Universität - Mainz GPA: Summa Cum Laude
Chemistry Summa Cum Laude
Graduated with Honors
Graduated Magma Cum Lade
Dissertation: Engineered Multifunctional Nano Tools for Biological and Cancer Applications:
M.Sc: Chemistry, 1 2004 of Materials, Johannes Gutenberg Universität - Mainz Chemistry Synthesis and Biofunctionalization of Nanostructures
B.Sc: Chemistry, 1 2000 Osmania University - Hyderabad Chemistry