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CNS Sr. Research Associate Resume Example

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CNS SR. RESEARCH ASSOCIATE
Professional Summary

Out of a passion to improve the well-being of society through biomedical research, I specialized in molecular and cellular neurobiology and applied this to the study ofneurodegeneration. My objective is to expand our understanding of disease and advance diagnostic and therapeutic efforts. I am a highly self-motivated individual with over 7 yrs experience currently seeking to apply my extensive scientific training to new opportunities in biomedical research.

Skills
  • General Skills
    Grant & Protocol Writing
    Verbal Presentations/ Public Speaking
    Managing Multiple Projects Simultaneously
    Creative Problem Solving
  • Advanced Skills
    IACUC protocols, Animal Handling, Husbandry, and Perfusions
    Cellular Models: Primary Mammalian Cells, Cancer Cells, and Organotypic Slices
    Gene Therapy: AAV Design and ICV Delivery
    Molecular Cloning & Plasmid Design
    Microscopy: Fluorescent and Confocal
Work History
CNS Sr. Research Associate , 02/2020 to Current
Spark Therapeutics – City , STATE
  • Experimental design, execution and data analysis for CNS-directed research programs.
  • Initiates and oversees joint programs with internal and external collaborators.
  • Assist CNS research team in developing and running assays for early discovery and pre-clinical programs.
  • Assist CNS research team with in vitro and in vivo studies: perform routing assays including data analysis and data interpretation
Biomedical Research Assistant, 06/2016 to 02/2020
Mayo Clinic – City , STATE
  • Breeding and implementing transgenic mouse models to study neurodegenerative disease
  • Finalist in the 2019 Mayo Clinic and Florida Space Medicine Research Program "Micogravity Pitch Competition", my team is working to model and study aspects of neurological diseases in microgravity.
Doctoral Research, 08/2013 to 12/2019
Emory University & Mayo Clinic – City , STATE
  • Applied multi-omic approaches to study neurodegeneration in mouse models of disease
  • Used diverse biochemical approaches to answer disease relevant questions in animal and cell models
  • Designed and coordinated Institutional Animal Care and Use Committee (IACUC) approved protocols
  • Well-versed in animal handling, husbandry, and use Supervised and instructed technicians and students in scientific methodology and ethical practices
  • Communicated the significance of this research through peer-reviewed publications and numerous research conferences
  • Assisted with Neuroscience curriculum design and teaching for Emory undergraduate courses
  • Managed lab safety training and maintenance including, but not limited to: Biochemical and hazardous waste use and disposal

Technical Skills: Immunohistochemistry, RNA isolation and knock down (shRNA), Transcriptomics, Proteomics, Wide-field microscopy (Nikon), Culture and transfection of primary mouse motor neurons and neuroblastoma cell lines, Design and administration of AAV vectors to primary cells, ex vivo brain slices, and mouse models. Writing and managing IACUC protocols for the handling and use of mouse colonies.

Post-baccalaureate Research Student, 06/2012 to 07/2013
Emory University – City , STATE
  • Applied cutting-edge microscopy techniques to examining the contributions of mRNA binding proteins to the regenerative abilities of sensory neurons within an in vitro spinal cord injury paradigm
  • Presented the results of this project at several renown conferences and results are being prepared for peer-reviewed publication

Technical Skills: Immunohistochemistry, animal husbandry, wide field and confocal microscopy (Olympus and Ziess), live cell imaging (Nikon), fluorescence microscopy, polymerase chain reaction (PCR), histology, adult mouse spinal cord extraction, and harvesting and culturing of adult mouse dorsal root ganglia

Education
Ph.D.: Neuroscience, 12/2019
Emory University - City, State
  • Dissertation: Characterization of Motor Neuron-specific mRNA processing defects in a mouse model of Spinal Muscular Atrophy
  • Graduated with 3.8 GPA
  • Awarded Ruth L. Kirschstein National Research Service Award (NRSA)- NIH F31 NS098764-02
  • Awarded Emory University Neuroscience Institute Training Grant (T32)- NIH
  • Received Frontiers in Aging and Regenerative Research, University of Pittsburgh: Travel and Stipend Award (2013-2014)
No Degree: NeuroscienceMayo Clinic - City
  • Continuing education in Grant Writing and R-studio programming
Bachelor of Science: Biology, 05/2012
Sam Houston State University - City, State
  • Minored in Psychology
  • Graduated with 3.4 GPA
Internships

Company: Silma (2019)
Interned directly with the co-founder to assess strategies for customer discovery and market penetration for a startup biotech company in the US.
Skills: Performed Market Analysis. Developed unique outreach and customer discovery strategies. Refined business model

Albert Ludwigs University of Freiburg (2013)
Optimized the differentiation capabilities of neuroblastoma cell lines into functional dopaminergic neurons.
Used immunohistochemistry and flow cytometry to compare tyrosine hydroxylase expression patterns between different neuroblastoma lines.
Determined differentiation efficiency of induced pluripotent stem cell-derived dopaminergic neurons.
Skills: Immunocytochemistry, cell culture, flow cytometry, Fluorescence-activated cell
sorting (FACS), and stem cell maintenance and differentiation

University of Maryland Baltimore County (2011)
Investigated the role of Syndecan-1 protein in the development of locomotive abilities in developing drosophila melanogaster
Skills: RNA isolation, larval locomotor assays, tissue dissection, and qPCR
developing drosophila melanogaster
Skills: RNA isolation, larval locomotor assays, tissue dissection, and qPCR

Publications
  • Price PL, Morderer D, Rossoll W. 2018. RNP Assembly Defects in Spinal Muscular Atrophy. Adv Neurobiol.
  • Khalil B, Morderer D, Price PL, Liu F, Rossoll W. 2018. mRNP assembly, axonal transport, and local translation in neurodegenerative diseases. Brain Research
  • Price PL, Engel K, Tsia C, Talifero M, DiDonato C, Bassell G & Rossoll W. 2019. Characterization of Motor Neuron-specific mRNA processing defects in a mouse model of Spinal Muscular Atrophy. (In Preparation)
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Resume Overview

School Attended

  • Emory University
  • Mayo Clinic
  • Sam Houston State University

Job Titles Held:

  • CNS Sr. Research Associate
  • Biomedical Research Assistant
  • Doctoral Research
  • Post-baccalaureate Research Student

Degrees

  • Ph.D. : Neuroscience , 12/2019
    No Degree : Neuroscience
    Bachelor of Science : Biology , 05/2012

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