Hands-on experiance in clinical studies in swine, cattle and poultry
Expertise in protective antigen recovery, recombinant protein expression, and viral vector delivery system
Virology-Virus isolation, purification, and quantification
Chromatin immuno precipitation assays
Expertise in handling of laboratory animal models
Strong verbal and written skills in communicating complex technical information
Excellent interpersonal and supervisory skills
Organization skills- Co-Chair, Career Fair, 13th Annual Young Investigator's Colloquium, National Cancer Institute, NIH, 2013
Member,Organizing committee, Department of Biotechnology, Govt. of India sponsored short-term training course, Division of Animal Biotechnology, IVRI, 2007
Postdoctoral FellowNational Cancer Institute, National Institutes of Health - 9000 Rockville Pike, Bethesda, MD 20892.09/2009 - Current Project 1. Currently working on the project focused on elucidation of epigenetic regulation of KSHV life cycle by histone deacetylases. Project 2. Generated hypoxia-inducible factor (HIF)-1alpha, -2 alpha stable knock out BC3 (KSHV-infected suspension cell line) for use as in-vitro models to study the host-virus interactions affecting the KSHV life cycle. Project 3. Explored the mechanisms that up
regulate the expression of viral Latency associated nuclear antigen ( Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein) in cells in hypoxia.
Project 4. Collaborative project on the characterization of the
activation of protein tyrosine phosphatase, receptor type, Z polypeptide
(PTPRZ1) by hypoxia inducible factor-2 alpha.
Supervisor: Dr. Robert Yarchoan, MD
Postdoctoral FellowDivision of Biological Sciences, University of Chicago - 5801 S Ellis Ave Chicago, IL 60637.10/2008 - 09/2009 Project 1. Explored
the role of histone deacetylase; SIRT6, cellular protein in protecting the heart from hypertrophic
stimuli using cell culture and mouse models.
Project 2. Contributed to the discovery that Nicotinamide Adenine Dinucleotide protects the heart from hypertrophic stimuli. Supervisor: Dr. Mahesh Gupta. PhD
Ph.D.: Animal BiotechnologyDivision of Animal Biotechnology, Indian Veterinary Research Institute. - Izatnagar-Bareilly 243122. UttarPradesh, India.2008 Project 1: Elucidation of Apoptotic pathways induced by Newcastle disease virus in infected cells. Project 2: Development of recombinant DNA vaccine for Newcastle disease. Project 3: Development of diagnostic assay for the detection of classical swine fever virus infection. Supervisor: Dr. Ashok. K. Tiwari. PhD
Master of Science: Animal BiotechnologyDepartment of Biotechnology, College of Veterinary Sciences, G.B. Pant University of Agriculture and Technology. - Pantnagar 263145. Uttrakhand, India.2004 Project: Explored the Immunotoxicological
effects of commonly used pesticides using cell culture and in vivo models. Supervisor: Dr. R.S. Chauhan. PhD
Bachelor of Science: Veterinary and Animal SciencesVeterinary College, Karnataka Veterinary, Animal and Fisheries Sciences University - Nandinagar. Bidar 585401. Karnataka, India.2001 Project: Worked on the project on compilation of update on etiology, pathogenesis, diagnosis, and treatment of Bovine mastitis. Internship Coordinator: Dr. B.V. Shiva Prakash. PhD
for American College of Veterinary Microbiologists (ACVM) specialization in
Virology certification by examination. Examination due in December 2013.
Honors and Awards
Awarded with honor in recognition of service for
organizing the 13th Annual Young Investigator's Colloquium, NCI,
Recipient of Ramalingaswami Fellowship-2012 from
Department of Biotechnology, Govt. of India.
Co-Chair, Career Fair, 13th Annual Young
Investigator's Colloquium, National Cancer Institute, NIH, Bethesda, 2013.
Co-Chair, Workshop on “ Careers in Science Writing”
13th Annual Young Investigator's Colloquium, National Cancer
Institute, NIH, Bethesda, 2013.
Travel grants award. National Cancer Institute,
Visiting Fellowship. National Cancer Institute.
Postdoctoral fellowship. University of Chicago.
Indian Society for Veterinary Immunology and
Biotechnology (ISVIB) - Scientist award. Pantnagar. India. 2007.
Travel grants award. Prof. Tielen Foundation.
Tartu. Estonia. 2007.
Young scientist award. Society for Immunology &
Immunopathology (SIIP), Chennai. India. 2007.
Senior Research fellowship. University Grants
Commission (UGC). Govt. of India. 2007-2008.
Travel grants award. European Academy of Allergy
and Clinical Immunology. Munich. Germany. 2005.
Junior Research Fellowship. University Grants
Commission (UGC). Govt. of India. 2004-2006.
Junior research fellowship. ICAR sponsored National
Fellow Project. Pantnagar. India. 2003-2004
Merit Scholarship. S.J. Jindal Trust. Bangalore. India. 1996-2001.
N. R. Sundaresan et al., The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun. Nature medicine 18, 1643 (Nov, 2012).
R. P. Veeranna, M. Haque, D. A. Davis, M. Yang, R. Yarchoan, Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induction by hypoxia and hypoxia-inducible factors. Journal of virology 86, 1097 (Jan, 2012).
V. Wang, D. A. Davis, R. P. Veeranna, M. Haque, R. Yarchoan, Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha. PloS one 5, e9641 (2010).
V. B. Pillai et al., Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. The Journal of biological chemistry 285, 3133 (Jan 29, 2010).
*P. V. Ravindra et al., Time course of Newcastle disease virus-induced apoptotic pathways. Virus research 144, 350 (Sep, 2009).
*P. V. Ravindra et al., Newcastle disease virus-induced cytopathic effect in infected cells is caused by apoptosis. Virus research 141, 13 (Apr, 2009).
*P. V. Ravindra, A. K. Tiwari, B. Sharma, R. S. Chauhan, Newcastle disease virus as an oncolytic agent. The Indian journal of medical research 130, 507 (Nov, 2009).
P. V. Ravindra et al., Induction of apoptosis in Vero cells by Newcastle disease virus requires viral replication, de-novo protein synthesis and caspase activation. Virus research 133, 285 (May, 2008).
P. V. Ravindra et al., HN protein of Newcastle disease virus causes apoptosis in chicken embryo fibroblast cells. Archives of virology 153, 749 (2008).
*P. Kote, V. Ravindra, R. S. Chauhan, P. Kote, V. Girish, Use of avian lymphocytes to detect toxicity: effects of a commonly utilized deltamethrin preparation. Journal of immunotoxicology 3, 101 (Jul 1, 2006).
U. Chaturvedi et al., Development and in vitro characterization of a bivalent DNA containing HN and F genes of velogenic Newcastle disease virus. Indian journal of experimental biology 49, 140 (Feb, 2011).
B. Ratta et al., Characterization and expression of e2 glycoprotein of classical Swine Fever virus in a eukaryotic expression system. Indian journal of virology : an official organ of Indian Virological Society 21, 69 (Jun, 2010).
Y. S. Rajawat et al., Immune responses induced by DNA vaccines encoding Newcastle virus haemagglutinin and/or fusion proteins in maternal antibody-positive commercial broiler chicken. British poultry science 49, 111 (Mar, 2008).
U. Chaturvedi et al., Detection of canine adenoviral infections in urine and faeces by the polymerase chain reaction. Journal of virological methods 149, 260 (May, 2008).
N. R. Sundaresan et al., Cytokines and chemokines in postovulatory follicle regression of domestic chicken (Gallus gallus domesticus). Developmental and comparative immunology 32, 253 (2008).
V. K. Nagaleekar et al., Bluetongue virus induces apoptosis in cultured mammalian cells by both caspase-dependent extrinsic and intrinsic apoptotic pathways. Archives of virology 152, 1751 (2007). * Corresponding author
Selected presentations in conference/symposium
conference on malignancies in AIDS and other acquired immunodeficiencies
(ICMAOI). Lister Hill center auditorium. NIH campus, Bethesda, MD. Nov., 7-8,
14th annual HIV Drug
Resistance Programme Think Tank Meeting. NCI Frederick, MD. April., 2011 (Oral)