Senior Research Scientist resume example with 20 years of experience

Jessica Claire
  • Montgomery Street, San Francisco, CA 94105 609 Johnson Ave., 49204, Tulsa, OK
  • H: (555) 432-1000
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  • Date of Birth:
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Career Overview

I have successfully shifted my studies from the agricultural field to the medical field after I got my PhD in 2000. Because I am very interested in cancer research, I have continued working in that area for more than 15 years. My research focus is on prostate cancer. Through these many years of research experience, I have developed an excellent proficiency in cancer research with broad scopes of both in vitro and in vivo, from cell cultures to animal models. My strongest skills include adapting, developing, and troubleshooting. For a new or tough project, I am able to figure out the key issue by searching the references and analyzing critically. This way, I can tackle the problems and work out the best possible solutions. That is why I may forge ahead in the field of cancer research even when it was not my original expertise.

Since I moved to NYU from WFU, I have been working on patient specimen for immunoprofiling, PDOTs(patient-derived organotypic tumor spheroids) isolation and drug treatment. I have grasped more specific techniques for clinical specimen processing and analysis. I has successfully developed syngeneic mouse organoid model for prostate cancer preclinical study. Also I am involved in lung cancer mouse models, thus enriched much more expereince(dosing, MRI, sample collection, etc) for preclinical studies.

Professional Skills
  • Cancer organoids and PDOTs( (patient-derived organotypic tumor spheroids) culture: mouse organoids isolation, CRISPR/cas9 gene editing, PDOTs isolation and drug treatment
  • Preclinical study: Xenograft and Allograft tumor cell implantation, tumor measurement, Imaging(MRI, Ultrasound, Bioluminescence), dosing(PO, IP, SC, IV), blood collection, necropsy with tissue collection for analysis.
  • Cancer Cell Biology: human and mouse cell culture, gene transfection, cell cycle, cell proliferation assay, apoptosis, cell signaling pathway, etc.
  • Mouse Model: development, colony breeding , genotyping, Xenograft, Allograft, Syngeneic, GEMM, micro-dissection, etc.
  • Molecular and biochemical biology: DNA, RNA, protein, real time PCR, gene microarray, cytokine array, Western Blot, Northern Blot, Southern Blot, etc.
  • IHC/IF and H & E: tissue staining, evaluation, etc.
  • Flow Cytometry: BD Fortessa, Flow Calibur, Canto II, Accuri C6, surface marker staining, intra cellular staining, multiple color staining, FlowJo, FCS Express, for mice tissue, human blood and patient specimen.
  • Immunology: T cell, B cell, adoptive immune cell transfer, TIL isolation, cytokine assay, etc.
  • Cancer Stem Cell: Isolation, stem cell culture, sphere assay, tumorigenicity, etc.
  • Bio-statistics analysis: GraphPad , ANOVA , etc.
Professional Experience
Senior Research Scientist, 01/2018 - Current
Fm Global North Olmsted, OH,

1. Prostate and lung cancer patient specimen: processing, PDOTs
culture and drug treatment and efficacy analysis, Immunoprofiling
2. Preclinical study: lung cancer mouse model: breeding, dosing, adenovirus
nasal induction, ultrasound guiding thoracic tumor cell injection. MRI and quantification.
3. Prostate cancer modeling: Organoids isolation from cas9 mice and GEMM mice prostate, tumor suppression gene manipulation(CAS9/CRISPR) and Myc overexpression, Allograft implantation, tumor imaging (MRI, ultrasound and Bioluminescence)
4. MDOTs(murine-derived organotypic tumor spheroids) - drug treatment and immunoprofiling
5. Lab management: paper work(animal IACUC protocol,IBC), ordering

Research Associate, 08/2004 - 01/2018
Engine Group Princeton, NJ,
  • Project 1- Diet(omega-3 & omega-6) and Prostate Cancer- PTEN and LOX or COX double knockout mice model
  • Project 2 - Inflammation and Prostate Cancer (1)Rag1 and PTEN double knockout mice model, Bone marrow adoptive transfer (2)CD4 and PTEN double knockout mice model (3)CD8 and PTEN double knockout mice model (4)Jh and PTEN double out mice model
  • Project 3 - Dip13beta(APPL2) gene konockout mice
  • Project 4 - PTEN knockout and p53 mutation and Prostate Cancer Metastasis
  • Project 5 High Myc mice model -Prostate cancer
  • Project 6 PERK and Prostate cancer-PTEN and PERK double knockout
  • Project 7 SDC1 and Prostate cancer-PTEN and SDC1 double knockout
  • Project 8 Prostate cancer stem cell- stem cell isolation from FASN and ABCA1 and PTEN Triple knockout mice, sphere assay, tumorigenecity, tissue regeneration.
Post-Doctoral Research Fellow, 04/2002 - 07/2004
Massachusetts General Hospital Woburn, MA,
  • Project - Dip13alpha(APPL1) and Dip13beta (APPL2) and cell cycle arrest.
Research Scholar, 03/2001 - 03/2002
Duke University Wake Forest, NC, Soil microbe and plant pathology
Education and Training
Ph.D.: Molecular Plant Pathology, Expected in 2000
Nanjing Agricultural University - Nanjing, Jiangsu Province
Master of Science: Molecular Plant Pathology, Expected in 1993
Nanjing Agricultural University - Nanjing, Jiangsu Province
Bachelor of Science: Biology, Expected in 1988
Anhui Normal University - Clairehu, Anhui Province

*Caner Biology Honor, Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA (2011).

*Science and Technology Advance Award, Jiangsu Province Science and Technology Committee, Jiangsu Province, P.R.China (1999).

*Excellent Research Paper Award, Nanjing Agricultural University, Jiangsu Province, P.R.China (1997).

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Resume Overview

School Attended

  • Nanjing Agricultural University
  • Nanjing Agricultural University
  • Anhui Normal University

Job Titles Held:

  • Senior Research Scientist
  • Research Associate
  • Post-Doctoral Research Fellow
  • Research Scholar


  • Ph.D.
  • Master of Science
  • Bachelor of Science

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