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Research Scientist II Resume Example

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RESEARCH SCIENTIST II
Professional Summary
An applied mathematician with strong scientific, computer, and analytical skills. A fast learning multitasker with excellent oral and written communication skills. 8+ years of research experience in computational and experimental biology. Proven publication record in high profile scientific journals. Self-motivated, enthusiastic, with positive attitude and strong work ethics.
Publications
5 of 27) Shivendra Tewari, Scott Bugenhagen, Kalyan Vinnakota, Jeremy Rice, Paul Janssen, Daniel Beard (2016), Influence of metabolic dysfunction on cardiac mechanics in decompensated hypertrophy and heart failure, J Mol Cell Cardiol 94: 162-175. [IF: 5.5] Shivendra Tewari, Scott Bugenhagen, Bradley Palmer, Daniel Beard (2016), Dynamics of cross-bridge cycling, ATP hydrolysis, force generation, and deformation in cardiac muscle, J Mol Cell Cardiol 96: 11-25. [IF: 5.5] Shivendra Tewari, Amadou Camara, David Stowe, Ranjan Dash (2014), Computational Analysis of Ca2+ Dynamics in Isolated Cardiac Mitochondria Suggests Two Distinct Modes of Ca2+ Uptake, J Physiol, 592 (9): 1917-1930. [IF: 5.2] Shivendra Tewari, Scott Bugenhagen, Brian Carlson, Naomi Chesler, Daniel Beard (2013), Analysis of cardiovascular dynamics in pulmonary hypertensive C57BL6/J mice, Front Physiol 5:513. [IF: 3.9] Shivendra Tewari, Ranjan Dash, Daniel Beard, Jason Bazil (2012), A Biophysical Model of the Mitochondrial ATP- Mg/Pi Carrier, Biophys J 103(7): 1616­1625. [IF: 3.5]
Skills
Work History
Research Scientist II, 10/2015 to Current
Company Name – City, State
  • Integrate gene transcription data obtained under physiological and pathological conditions with genome-scale metabolic network to: (1.) predict condition specific phenotype and (2.) identify genes underlying the pathological response. Supervisor: Dr. S. Anders Wallqvist.

Postdoctoral Fellow, 09/2013 to 10/2015
Company Name – City
  • To simulate integrated cardiovascular function of the rat, and build validated computer models that account for genetic.
  • variation across rat strains and physiological response to environment (e.g., stress).
  • Supervisor: Dr.
  • Daniel A Beard.
  • To develop multi-scale model of human myocardium and test the effect of drugs on human myocardium mechanics and.
  • whole-body phenotype.
  • Collaborator: Dr.
  • Tetsuro Wakatsuki (Invivo Sciences Inc., Madison, WI).
Postdoctoral Fellow, 01/2012 to 08/2013
Company Name
  • Developing cardiovascular bio-mechanics and hemodynamics modeling of invivo ventricular pressure-volume data in order to identify differences among control and hypertensive animals.
  • Supervisor: Dr.
  • Daniel A Beard Modeling isolated cardiac mitochondrial calcium handling experiments using an integrated model of oxidative phosphorylation and cation handling to gain a quantitative and biophysical understanding of the underlying process involved in calcium transport and buffering in the matrix.
  • Supervisor: Dr.
  • Ranjan K Dash Mitochondrial ion channel identification using patch-clamping of mitoplasts and characterization using Bayesian inference based methods such as Markov chain Monte Carlo.
  • Collaborator: Dr.
  • Wai-Meng Kwok.
Visiting Scientist, 03/2013
Company Name – City
  • Isolation of mitochondrial inner and outer membrane from mice heart, and it's reconstitution in proteo-liposomes.
  • Patch-.
  • clamping of the reconstituted proteoliposomes.
  • Supervisor: Dr.
  • Kathleen C Kinnally.
  • Preparation of mice heart mitoplasts using French press method and osmotic shock method.
  • Patch-clamping of the.
  • isolated mitoplasts.
  • Supervisor: Dr.
  • Kathleen C Kinnally.
Postdoctoral Fellow, 01/2011
Company Name – City
  • Biophysically detailed modeling of astrocyte-neuron interaction at hippocampus with special relevance to short-term and.
  • long-term synaptic plasticity (molecular correlate of learning and memory).
  • Supervisor: Dr.
  • Kaushik K Majumdar.
Research Fellow, 01/2007
Company Name – City
  • Developed spatio-temporal mathematical models governing Ca2+ dynamics in neurons, and pseudo-analytic method for.
  • obtaining solution of parabolic partial differential equation.
  • Supervisor: Dr.
  • Kamal Raj Pardasani.
Interests
14th Annual Conference of Gwalior Academy of Mathematical Sciences (GAMS) With Symposium on Computational Mathematics and its Application to Engineering, Management and Biology held during July 17-19, 2009 at IPS College of Technology and Management, (IPS CTM), Gwalior, India. Institute Research Fellowship 2007 ­ 2010 Awarded by National Institute of Technology, Bhopal, India. RESEARCH PROJECTS Got one Research Project, as Principal Investigator, entitled "Spatio-temporal study of the tripartite synapse" sanctioned by Department of Science & Technology (Government of India), file no. SR/CSI/PDF-13/2011, of an amount of Rs. 10,40,000 for a duration of two years. SELECTED TALKS Delivered a talk titled "Biophysically based model of cross-bridge cycling and cardiac muscle force generation predicts A-, B-, and C-process of sinusoidal analysis" at Oakland University on September 13, 2014 in Rochester, MI. Delivered a talk titled "Analysis of Cardiovascular Dynamics in Pulmonary Hypertensive C57BL6/J Mice" at SIAM Conference on the Life Sciences during August 4 ­ 7, 2014 in Charlotte, USA. Delivered a talk titled "Insights into right ventricular dysfunction through 1-D modeling of pulmonary circulations" at 7th World Congress of Biomechanics during July 6-11, 2014 in Boston, USA. PROFESSIONAL SKILLS Dry Lab MATLAB, Mathematica, XPPAUT, STochastic Engine for Pathway Simulation (STEPS) Wet Lab Cell culture, Cell electrophysiology (whole-cell, single-channel), Isolation of mitochondria, mitochondrial membranes (outer/inner) from cultured cells and tissues, Mitochondrial electrophysiology (single-channel), Proteoliposome electrophysiology (single-channel).
Additional Information
  • HONORS and AWARDS Cognitive Science Initiative Postdoctoral Fellowship 2011 Awarded by Department of Science & Technology, Ministry of Science amp; Technology, Government of India. Best Paper Award (ISTAM Gold Medal) 2010 55th Congress of Indian Society of Theoretical and Applied Mechanics An International meet) ­ ISTAM 2010 held during 18-21 December, 2010 at National Institute of Technology, Hamirpur, India. Young Scientist Award 2009 14th Annual Conference of Gwalior Academy of Mathematical Sciences (GAMS) With Symposium on Computational Mathematics and its Application to Engineering, Management and Biology held during July 17-19, 2009 at IPS College of Technology and Management, (IPS CTM), Gwalior, India. Institute Research Fellowship 2007 ­ 2010 Awarded by National Institute of Technology, Bhopal, India. RESEARCH PROJECTS Got one Research Project, as Principal Investigator, entitled "Spatio-temporal study of the tripartite synapse" sanctioned by Department of Science & Technology (Government of India), file no. SR/CSI/PDF-13/2011, of an amount of Rs. 10,40,000 for a duration of two years. SELECTED TALKS Delivered a talk titled "Biophysically based model of cross-bridge cycling and cardiac muscle force generation predicts A-, B-, and C-process of sinusoidal analysis" at Oakland University on September 13, 2014 in Rochester, MI. Delivered a talk titled "Analysis of Cardiovascular Dynamics in Pulmonary Hypertensive C57BL6/J Mice" at SIAM Conference on the Life Sciences during August 4 ­ 7, 2014 in Charlotte, USA. Delivered a talk titled "Insights into right ventricular dysfunction through 1-D modeling of pulmonary circulations" at 7th World Congress of Biomechanics during July 6-11, 2014 in Boston, USA. PROFESSIONAL SKILLS Dry Lab MATLAB, Mathematica, XPPAUT, STochastic Engine for Pathway Simulation (STEPS) Wet Lab Cell culture, Cell electrophysiology (whole-cell, single-channel), Isolation of mitochondria, mitochondrial membranes (outer/inner) from cultured cells and tissues, Mitochondrial electrophysiology (single-channel), Proteoliposome electrophysiology (single-channel).
Education
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