Internationally recognized business-oriented Medical Research and Development Professional in the Neurosciences, Psychiatry, Neurology, Sleep Medicine areas seeking a Research and Development position in the pharmaceutical industry offering 12 years background as Founder and Chief Medical Officer for Ebb Therapeutics, a medical device company with successful exit in 2020 (merger with combined business valued at ~$130M), 17 years Professor at University of Pittsburgh School of Medicine and 3 years President of the Sleep Research Society. Proven expertise in leading all clinical trial and research activities including data analysis and publication to support product development, FDA clearance, sales and marketing teams to commercialize technology. International expertise in academic clinical research. Having developed a reputation for using hard work, creativity, and leadership to produce better results. Possess an in-depth understanding of Project management, and the know-how of budget and management of multiple projects ensuring all priorities are accomplished. Demonstrated ability to lead others toward the critical issues at hand to develop successful solutions. Recognized consistently for performance excellence and contributions to success.
NIMH Research Fellow in Psychiatry
Board Certified Sleep Specialist
American Board of Sleep Medicine
Diplomat in Psychiatry
American Board of Psychiatry and Neurology
Sol Ginsburg Fellow - Group for the Advancement of Psychiatry 1988-1990; NIMH Outstanding Resident 1989; APA/DISTA Products Resident Research Award 1990-1991; Ethel Ginsburg Fellow - Group for the Advancement of Psychiatry 1991; Research chosen by National Center for Research Resources (NCRR) to be summarized for the Congressional Hearings on the FY2001 NIH budget; Chairman, Training and Education Activities Committee of the Sleep Research Society 2002; Board Member, Sleep Research Society 2002-2006; Vice-Chair of the Research Committee of the American Academy of Sleep Medicine 2003-2004; Chair, “Sleep Disorders” section of the Sleep Research Society 2003-2004; Member, Program Committee of the Association for Professional Sleep Societies 2003-2006; Invited Member of Review Committee for the National 2005 Center for Research Resources Brain Imaging Research Network (BIRN) Proposal; Nominated to serve as Treasurer, Sleep Research Society; President, Sleep Research Society 2006-2009; President, Sleep Research Society Foundation 2009; Pitt “Innovator” Award 2011; Pitt “Innovator” Award 2012
Pfizer; Sepracor; Johnson and Johnson; Somaxon; Actelion; Merck; Eli Lilly; Technogel; Eisai; Sanofi; Janssen;
Nofzinger EA, Thase ME, Reynolds CF, Himmelhoch JM, Mallinger A, Houck P and Kupfer DJ: Hypersomnia in bipolar depression: A comparison with narcolepsy using the multiple sleep latency test. American Journal of Psychiatry, 148(9):1177-1181, 1992. Nofzinger EA, Buysse DJ, Reynolds CF 3rd and Kupfer DJ: Sleep disorders related to another mental disorder (nonsubstance/primary): A DSM IV Literature Review. Journal of Clinical Psychiatry, 54(7):244-259, 1993. Nofzinger EA, Reynolds CF 3rd, Thase ME, Frank E, Jennings JR, Fasiczka AL, Sullivan LR and Kupfer DJ: REM sleep enhancement by bupropion in depressed men. The American Journal of Psychiatry, 152(2):274-276, 1995. Nofzinger EA, Mintun MA, Wiseman M, Kupfer DJ and Moore RY: Forebrain activation in REM sleep: An FDG PET study. Brain Research, 770:192-201, 1997.Nofzinger EA, Mintun MA, Price J, Meltzer CC, Townsend D, Buysse DJ, Reynolds CF 3rd, Dachille M, Matzzie J, Kupfer DJ and Moore RY: A method for the assessment of the functional neuroanatomy of human sleep using FDG PET. Brain Research Protocols, 2(3):191-198, 1998. Nofzinger EA, Nichols TE, Meltzer C, Price J, Steppe DA, Miewald JM, Kupfer DJ and Moore RY: Changes in forebrain function from waking to REM sleep in depression: Preliminary analyses of [18F] - FDG PET studies. Psychiatry Research: Neuroimaging, 91(2):59-78, 1999. Nofzinger EA: Insights from functional neuroimaging studies of behavioral state regulation in healthy and depressed subjects. Behavioral and Brain Sciences, 23(6):979-980, 2000. Nofzinger EA, Fasiczka A, Berman S and Thase ME: Bupropion SR reduces periodic limb movements that are associated with arousals from sleep in depressed patients with periodic limb movement disorder (PLMD). Journal of Clinical Psychiatry, 61:858-862, 200 Nofzinger EA, Price JC, Meltzer CC, Buysse DJ, Villemagne VL, Miewald JM, Sembrat RC, Steppe DA and Kupfer DJ: Towards a neurobiology of dysfunctional arousal in depression: the relationship between beta EEG power and regional cerebral glucose metabolism during NREM sleep. Psychiatry Research: Neuroimaging, 98:71-91, 200. Nofzinger EA, Berman S, Fasiczka A, Miewald JM, Meltzer CC, Price JC, Sembrat RC, Wood A, and Thase ME: Effects of Bupropion SR on anterior paralimbic function during waking and REM sleep in depression: preliminary findings using [18F]-FDG PET. Psychiatry Research: Neuroimaging, 106 (2):95-111, 2001. Nofzinger EA, Buysse DJ, Miewald JM, Meltzer CC, Price JC, Sembrat RC, Ombao H, Reynolds CF, Monk TH, Hall M, Kupfer DJ, and Moore RY: Human regional cerebral glucose metabolism during non-rapid eye movement (NREM) sleep in relation to waking. Brain, 125(Pt.5):1105-1115, 2002. Nofzinger EA, Buysse DJ, Germain A, Carter CS, Luna B, Price JC, Meltzer CC, Miewald JM, Reynolds CF, and Kupfer DJ: Increased activation of anterior paralimbic and executive cortex from waking to REM sleep in depression. Archives of General Psychiatry, 61(7):695-702, 2004. Nofzinger EA, Buysse DJ, Germain A, Price JC, Miewald JM, and Kupfer DJ: Functional neuroimaging evidence for hyperarousal in insomnia. American Journal of Psychiatry, 161(11):2126-2128, 2004. Nofzinger, EA: Regional cerebral metabolism in insomnia: Hierarchical levels of arousal. INSOM, 2005. Nofzinger EA, Buysse DJ, Germain A, Price JC, Meltzer CC, Miewald JM, and Kupfer DJ. Alterations in regional cerebral glucose metabolism across waking and NREM sleep in depression. Archives of General Psychiatry, 62(4):387-96, 2005. Nofzinger, EA, Nissen, C, Germain, A, Moul, D, Hall, M, Price, JC, Miewald, JM, and Buysse, DJ: Regional cerebral metabolic correlates of WASO during NREM sleep in insomnia. Journal of Clinical Sleep Medicine, 2(3):316-322, 2006. Roth T, Mayleben D, Feldman N, Lankford A, Grant T, Nofzinger E. A novel forehead temperature-regulating device for insomnia: a randomized clinical trial. Sleep. 2018 May 1;41(5). Mysliwiec V, Neylan TC, Chiappetta L, Nofzinger EA. Effects of a forehead cooling device in veterans with chronic insomnia disorder and co-morbid medical and psychiatric conditions: a pilot study [published online ahead of print, 2020 Jun 22]. Sleep Breath. 2020. Baker FC, de Zambotti M, Chiappetta L, Nofzinger EA. Effects of forehead cooling and supportive care on menopause-related sleep difficulties, hot flashes and menopausal symptoms: a pilot study. Behav Sleep Med. 2020 Oct 10:1-14. do10.1080/15402002.2020.1826484.86. on menopause-related sleep difficulties, hot flashes and menopausal symptoms: a pilot study. Behav Sleep Med. 2020 Oct 10:1-14. doi: 10.1080/15402002.2020.1826484.
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