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Bioinformatics Analyst Resume Example

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BIOINFORMATICS ANALYST
Professional Summary
I am skilled,sincere and result driven. Although I have good experience in working with Bioinformatics tools, I would always experiment and up for learning new techniques. Beside using various Analytical tools, Programming languages, relational databases as well as development/ maintenance of database, I am seeking a position where i can develop and excel while giving my best to an employer.

Bioinformatics Degree with a Management focus effective Communicator with strong documentation skills Summary of Skills
Skills
Bioinformatics Skills: 
 ● Nucleic acid as well as protein sequence and structure analysis, ClustalW, protein-protein interactions. 
 ● Profile searches, phylogenetic inference as well as Gene Expression Analysis having cluster analysis, visualization of expression data, Molecular Pathway Analysis and Network analysis, Sequence Annotation for Next Generation Sequencing using MEGA5.1,
Needleman-Wunsh Algorithm, VPhaser-2, HyPhy, Geneious, TreeViewer, Partek.

Management Skills:  
● Project Management, Negotiation, Analysis of IT industry, Company finance, Operation management

Computer Skills:
Perl Scripting, Learning Python,
Windows, Unix, Linux, Mac OSX,
SSH, R Console, FTP, Filemaker Pro.
Work History
08/2011 to Current
Bioinformatics AnalystInvitae – Iselin , NJ
  • Created 3 databases for the 3 different Core labs using Filemaker Pro which help making Brady labels and to store, process, share and analyze sample inventory ·      
  • Created the Drug Resistance database that Collected and analyzed individual drug resistance data and generated comparative drug resistance result for samples. ·      
  • Experience with illumina analysis techniques using Miseq for Next Generation Sequences  using VPhaser-2 tool to call variants and SNP's with quality control and overplots.
  •  Worked with various bioinformatics software's like VPhaser-2 (SNP's), HyPhy, ClustalW, MEGA 5, Sequencher, Partek, Tree viewer, Geneious etc .
  • As a quick learner i have learned most of the above software's and Database Programming on my own. I am currently learning BioPython.
01/2010 to 05/2011
Research AssistantSeattle Children's Hospital – Great Falls , MT
  • Focused on neurons within the hippocampus  
  • Performed Data mining from research journal literature focusing on connectivity between the Neurons and signals.  
  • Managed spreadsheets, articles of future interests, work logs, bibliography and assignments in the department
  • Maintained quality control across database information to find the most accurate information to help further research.
Education
2011
Master of Science: Bioinformatics Management
George Mason University - City, State
  • Coursework in Microarray, Perl Scripting, Biological Algorithm, Biochemistry.
2008
Bachelor of Science: Bioinformatics
Dr. D. Y. Patil University for Biotechnology and Bioinformatics - City, State
  • Emphasis in Perl Programming, Bioinformatics software's, Biochemistry, Oncology, Genomics, and many more.
2003
High School Diploma: Information Technology
National Institute of Information Technology - City, State
  • Coursework in SQL, JAVA, C++
Accomplishments
Poster Presentation
January 2011 to Current
Department of Bioinformatics,
George Mason University, Fairfax, VA

  • Annotated the Protein coding regions of Simian adenovirus gene 27.1 in comparison to Simian adenovirus 32 using Artemis. 
  • Analyzed the percentage identity of these coding regions for SAdV27.1 to the coding regions of 5 distinct and close Genome species using Needleman and Wunsch algorithm via EMBOSS. 
  • Generated a graphical visualization to find the closely related genome using the zpicture. 
  • Developed a phylogenetic tree based on the maximum likelihood algorithm using an bioinformatics software MEGA 5.
Project
August 2010 to December 2010
Department of Bioinformatics,
George Mason University, Fairfax, VA

  • Analyzed and Extracted dataset for normal and invasive breast cancer cells in stroma were from NCBI GEO. 
  • Conducted Microarray Expression Analysis: RMA Normalization,Exploratory analysis, Noise threshold analysis, Noise Filtering, Variance and Normality analysis, Significance Analysis, Gene selection and Molecular Pathway analysis.
Project
January 2010 to May 2010
Department of Computer Science,
George Mason University, Fairfax, Virginia

  • Focused on the Illumina sequencing platform that produces millions of very short sequences that are 35 bases in length.
  • Classified three assembler namely Edena, Abyss and Velvet for thissurvey. These assemblers were based on a classical overlap graph like De Bruijn graph, Overlap-layout- consensus graphs and on the detection of potentially spurious reads.
  • Compared assembly results of data sets for Staphylococcus aureus, Saccharomyces cerevisiae and Caenorhabditis elegans.  
  • Evaluated Assemblers on various factors like Number of contigs, Maximum Contig length, Minimum Contig Length, Mean Contig Length, N50, N80 and Runtime.
Final Project
January 2008 to May 2008
Dr. D.Y. Patil Institute for Bioinformatics
Navi Mumbai,Maharashtra, India.

  •  Developed for users to find various protein sequence length as well as protein sequences.
  • Scripted In Perl for the users to select the alpha and beta propensity values given to each protein residue in the  database for which the epitopes were predicted.The alpha and beta propensities values were values published by various research scientists and literatures. 
  • Led to accurate epitope prediction for the desired protein of interest.

Trainee  

January 2006 to March 2006  

Reliance Life Sciences Research Centre – Navi Mumbai, Maharashtra, India.

  • The objective was to clone a therapeutic protein (activating the cytokine) in order carry out immune response against cancer antigens  
  • Identified the gene coding for the cytokine from the literature, and isolated the tRNA from the animal cell line  
  • Prepared Reverse transcriptase (RT) PCR and the cDNA amplification using specific pre-designed primers.
  • Ligated of pUC19 vector into the gene followed by transformation into bacterial cells.
  • Performed Colony PCR to grow multiple cells. Processed the Restriction enzymes digestion using BamHI and EcoRI to find the insert.
  • Multiple Sequence Alignment was conducted using ClustalW software, showed one positive clone as the result.





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Resume Overview

School Attended

  • George Mason University
  • Dr. D. Y. Patil University for Biotechnology and Bioinformatics
  • National Institute of Information Technology

Job Titles Held:

  • Bioinformatics Analyst
  • Research Assistant

Degrees

  • Master of Science : Bioinformatics Management
    Bachelor of Science : Bioinformatics
    High School Diploma : Information Technology

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