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associate scientist resume example with 4+ years of experience

Jessica
Claire
resumesample@example.com
(555) 432-1000,
Montgomery Street, San Francisco, CA 94105
:
Professional Overview

Ambitious and independent biomedical engineer/scientist with a passion for immunotherapy and using biotechnology to advance patient care. With 5 years of diverse experience across immunology, cell and gene therapeutics, machine learning, and manufacturing. Leveraged skills in all these areas to optimize processes and design assays and analytical methods to drive progress on industry and academic projects. The most integrative projects being in optimizing a CRISPR gene editing and viral transduction pipeline for CAR-T/HIT T cell production, developing flow cytometry and imaging based assays for detecting fratricide, and developing an ML segmentation and phenotyping tool for tertiary lymphoid structures. With a growth mindset and the ability to manage many projects at once I am a persistent and proven effective collaborator; always looking to build avenues for scientific exchange within and across teams.

Education
NYU Tandon School of Engineering Brooklyn, NY, Expected in 05/2021 Master of Science : Biotechnology - GPA :
Western New England University Springfield, MA Expected in 05/2019 Bachelor of Science : Biomedical Engineering - GPA :
  • Concentration: Nanotechnology
  • Minor: Chemistry
  • Global Scholars Distinction
Summary of Qualifications
  • Flow cytometry: multicolor panel design, intracellular staining, flow based assays for lineage tracing, metabolism, cytokine detection (BD CBA)
  • Cell based assays: Cytotoxicity, fratricide, WISH, spheroid infiltration, assay development
  • Cell culture: Human, mouse, cell lines and primary cultures, three dimensional culture, biomimetic culture systems/multi-culture systems
  • Viral production and transduction: LVV, AAV, gRV, CAR-T and HIT constructs
  • CRIPSR-Cas9, Lonza electroporation system, cell engineering
  • PCR/qPCR, Western Blot, MaxiPrep, ELISA
  • Microscopy: frozen and paraffin tissue preparation, cryosectioning, IHC and IF staining, confocal microscopy, RNAScope, Leica scanning scopes, OMERO platform usage, 2D-4D visualization
  • In vivo: IACUC protocol generation, mouse handling/husbandry, IP/IV/RO injections, tissue collection, tamoxifen and controlled substance administration, AAALAC audit experience
  • Technical Writing: Develop/revise/execute SOPs & equipment validation protocols, log experimental procedure and results in ELN and technical reports
  • Analytical: Java, C++, R, Python, SQL, Tableau, MATLAB, COMSOL, FlowJo, ImageJ/Fiji, CellProfiler, Prism
Professional Experience
Covance - Associate Scientist
Scottsdale, AZ, 05/2021 - 02/2023
  • R&D level process development and SOP establishment for gene editing of human T cells and cell lines using CRISPR Cas9 associated with key technologies surrounding SUV, HIT, and target knock-outs on T cells
  • Process development/optimization for producing genetically modified human CAR-T/HIT T cells using gRV/LVV/AAV6 viral techniques and optimization of their associated assays in solid and liquid tumor contexts
  • End to end process execution from MaxiPrep of plasmids and generating viral producer lines to phenotyping and functional analysis of engineered T cells in vitro
  • Assay Development: fratricide, cytokine profiling, high throughput in vitro repeat challenge
  • Rapidly acquired expertise in HIT/HiTCR to lead arm optimization, cell production, and analysis for in vivo studies
  • SOP optimization and alignment with international teams between discovery and CMC
  • Trained newly hired employees on processes and procedures relevant to lab tasks
  • Contributed significantly to 3 patent applications
  • Helped build out laboratory in incubator space and transition to NY private laboratory working closely with the lab manager and other early scientists
  • Contributed to establishing company culture surrounding collaboration and scientific exchange between groups, provided IT support, established gene editing best practices, and helped to establish ELN best practices
NYU Langone Health - Niewold Lab - Assistant Research Technician/Lab Manager
City, STATE, 08/2019 - 05/2021
  • Performed all Lab Manager duties from November 14th, 2019- reagent ordering, managed inspections/audits for IACUC, AAALAC, and DEA
  • Performed administrative duties from March 15th, 2020- finances/invoicing, scheduling
  • Maintained mouse colony for SLE nephritis mouse model development, assisted with breeding strategy for Cre mice
  • Maintained human cell culture and performed cell-based assays to investigate interferon levels in human sera/plasma
  • Forged collaborations at NYU Tandon to develop biomimetic synovium-on-a-chip platform to replicate monocyte/macrophage infiltration in rheumatoid arthritis in 3D culture system

Image Analysis

  • Prepared mouse tissues, cut slides, and performed basic IHC and fluorescence staining protocols
  • Developed automated analysis protocols for segmenting and classifying cells in phenotypes of interest by registering IHC, IF, and RNAScope images for increased depth in analyses

Data Science

  • Managed team of Master’s students to develop UNet model for segmenting and classifying immune cell subsets, first author paper published Feb 2022: Artificial intelligence and deep learning to map immune cell types in inflamed human tissue
  • Designed applications of Semantic Web Technology to Machine Learning for RA patient treatment outcomes using EHR/clinical data interpretation: designed ontology, worked on data architecture, and assisted in project design and trajectory of future work
Gypsy Bay Genomics (now Basin Genomics) - Consultant on Strategic Communications Team
City, STATE, 05/2019 - 09/2019
  • Collaborated with internal and external stakeholders to identify key messages and create compelling content for press releases and other materials.
  • Developed website for the oncology biotech startup in collaboration with CEO
  • Curated educational resources to distill information for accessible scientific presentations to non-scientific audiences
Flex - Quality/Metrology Engineer
City, STATE, 06/2018 - 12/2018
  • Performed quality inspections using CMMs programmed systems using MeasureMind3D and Calypso
  • Performed process qualification, operational qualification, first article inspections
  • Maintained batch records and other technical documentation for products,
  • Created work instructions and training procedures in GD&T, SPC, fixture usage, performing statistical operations, data processing, and troubleshooting CMM errors
  • Followed GDP, ISO, and FDA regulatory guidelines for medical device manufacturing, implemented six sigma project protocols

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Resume Overview

School Attended

  • NYU Tandon School of Engineering
  • Western New England University

Job Titles Held:

  • Associate Scientist
  • Assistant Research Technician/Lab Manager
  • Consultant on Strategic Communications Team
  • Quality/Metrology Engineer

Degrees

  • Master of Science
  • Bachelor of Science

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