LiveCareer
LiveCareer
  • Dashboard
  • Jobs
  • Resumes
  • Cover Letters
  • Resumes
    • Resumes
    • Resume Builder
    • Resume Examples
      • Resume Examples
      • Nursing
      • Education
      • Administrative
      • Medical
      • Human Resources
      • View All
    • Resume Search
    • Resume Templates
      • Resume Templates
      • Nursing
      • Education
      • Medical
      • Human Resources
      • Customer Service
      • View All
    • Resume Services
    • Resume Formats
    • Resume Review
    • How to Write a Resume
    • CV Examples
    • CV Formats
    • CV Templates
    • Resume Objectives
  • Cover Letters
    • Cover Letters
    • Cover Letter Builder
    • Cover Letter Examples
      • Cover Letter Examples
      • Education
      • Medical
      • Human Resources
      • Customer Service
      • Business Operations
      • View All
    • Cover Letter Services
    • Cover Letter Templates
    • Cover Letter Formats
    • How to Write a Cover Letter
  • Jobs
    • Mobile App
    • Job Search
    • Job Apply Tool
    • Salary Calculator
    • Business Letters
    • Job Descriptions
  • Questions
  • Resources
  • About
  • Contact
  • 0Notifications
    • Notifications

      0 New
  • jane
    • Settings
    • Help & Support
    • Sign Out
  • Sign In
Member Login
  • LiveCareer
  • Resume Search
  • Staff Fellow
Please provide a type of job or location to search!
SEARCH

Staff Fellow Resume Example

Resume Score: 70%

Love this resume?Build Your Own Now
STAFF FELLOW
Professional Overview

Experienced scientific researcher with a wide-ranging skill set including a strong biochemistry and analytical chemistry background in addition to broad expertise in FDA regulation.

Skill Highlights
  • Protein expression (bacterial, mammalian and insect cells)
  • Protein detection and quantitation (SDS-PAGE, Western blot, ELISA, immunoprecipitation)
  • Tissue culture (adherent and suspension)
  • Protein functional assay design and optimization (binding and kinetic assays)
  • Protein Purification (affinity, ion exchange and size exclusion chromatography)
  • Experience with AKTA Purification systems and Unicorn software
  • X-ray Crystallography
  • Molecular modeling and docking programs (COOT, PyMol
  • Computer systems: UNIX, LINUX, Windows, MacOSX
  • Computer programs: GraphPrism, MacVector, MSoffice (including excel)
Experience
Staff Fellow
September 2009 to Current
FDA, Center of Biologics Evaluation and Research - Bethesda, MD
  • Review of Chemistry, Manufacturing and Control (CMC) aspects of original BLAs, supplements, Annual Reports and INDs of various Biologics products submitted to the Office of Blood Research and Review
  • Writing of memos covering review of process and viral clearance validation, stability, bioburden, sterility, extractable/leachables and other manufacturing processes impacting product quality, safety, potency and efficacy in a timely manner to meet deadlines.
  • Participation in meetings (Pre-IND, pre-BLA and other) with sponsor and preparing written responses to sponsor questions pertaining to CMC issues.
  • Conducted research involving understanding neutralizing antibodies against Hepatitis C virus
  • Developed a luciferase-based binding assay to understand viral antigen, host-cell receptor, and antibody interactions for vaccine design and as early stage potency assay.
  • Presented seminars relating to research results and regulatory topics to Division of Hematology
Undergraduate Research Assistant
July 1995
Wright State University - Dayton, OH
  • Synthesized peptide analogs containing spectroscopic probes for protein kinase studies.
Postdoctoral Fellow
June 2006 to July 2009
Medical Biotechnology Center - Baltimore, MD
  • Conducted research to elucidate the processes involved in neurodegenerative and protein aggregation diseases.
  • Studies focused on interactions of various proteins involved in the cellular process of ER-associated degradation (ERAD) and ubiquitin-proteasome protein degradation pathways.
  • Secondary duties of this position included mentoring graduate students and providing training and guidance to technicians in the laboratory.
Postdoctoral Research Associate
January 2006 to June 2006
Michigan State University - East Lansing, MI
  • Conducted structural and function studies of membrane proteins.
  • Research involved preparative scale protein expression using baculovirus system and preparative scale purification using various methods such as affinity, ion-exchange and size exclusion.
  • Studies also included performing crystallization trials using microbatch and vapor diffusion methods.
Graduate Research Assistant
January 1999 to January 2005
Michigan State University - East Lansing, MI
  • Thesis/ Dissertation: Studies focused on combining crystallographic techniques and kinetic analysis of substrate and inhibitor complexes with native and mutant Cyclooxygenases in order to understand substrate utilization and drug/protein interactions.
  • Studies resulted in two first author publications in the Journal of Biological Chemistry.
  • Research included DNA cloning, site-directed mutagenesis, protein expression in various cells lines including bacteria, insect and mammalian cells, protein purification, thin layer chromatography, protein crystallization and structure determination.
Graduate Research Assistant
January 1998 to January 1999
Purdue University - West Lafayette, MI
  • Studies focused on transcription, purification and crystallization of large catalytic RNAs to understand the mechanism of catalytic RNAs.
Analytical Chemist
January 1997 to January 1998
Mikart Inc - West Lafayette, MI
  • Method development and validation of analytical HPLC methods for various drug formulations containing multiple drug components.
  • Responsible for following GLP and GMP protocols.
  • Performed raw materials testing according to USP protocols.
Analytical Chemist
January 1996 to January 1997
Eurand America - West Lafayette, MI
  • Performed USP dissolution assays in combination with quantification of time-released drugs formulations using HPLC methods.
  • Performed validation of HPLC methods in compliance with GLP and GMP.
Research Assistant
January 1995 to January 1996
Southwestern Council for Higher Education - Dayton, OH
  • Synthesis, purification, and characterization of monomeric and polymeric materials at Wright Laboratories/Materials Directorate at Wright Patterson Air Force Base.
Specialty Training

•FDA/CBER New Reviewer Training Course: “The Lifecycle Approach” (4 day course) (Jan 14, 2009)

•FDA CBER OCBQ Manufacturing Technology Seminar: Single use upstream manufacturing including purification technologies and extractable leachables considerations (Feb 4, 2010)

•FDA CBER Analytical Technology Series Session 2 Proteomics: Principles and Methods (Feb 23, 2010)

•FDA CBER Manufacturing Process Science: Cell Culture, Fermentation and Bioreactor Technology (July 23, 1010)

•FDA CBER Manufacturing Process Science Series: Introduction to Downstream Processing Chromatography, Filtration, Precipitation & Centrifugation (Sept 23, 2011)

•FDA CBER Fundamentals of Bioassay Practices (Oct 27, 2011)

•FDA OCBQ Manufacturing Technology Seminar: Overview of Viral Clearance Technologies including virus inactivation at low pH, chromatography and nanofiltration (May 10, 2012)

•FDA OCBQ Manufacturing Technology Seminar: Basic Filtration including microfiltration, nanofiltration, and ultrafiltration (July 26, 2012)

•Technical Writing for Reviewers (Sept 10-11 )

•Biostatistics for Non-statisticians (3-day course) (Nov 13, 2012)

•FDA CBER Writing for Success using Plain Language (Mar 27, 2013)

•Basic Principles of Immunology and Hypersensitivity (audit FAES course NIH)

•Principles of Clinical Pharmacology (Clinical Center Sept 2, 2010-April 28, 2011-received certificate for 70% attendance of classes)

Education
Ph.D : Biochemistry and Molecular Biology, 2005Michigan State University - East Lansing, MI
  • Advisors: William L. Smith and R. Michael Garavito
B.S : Biology & Chemistry, 1996Wright State University - Dayton, OH
  • Double Bachelors degree in Biology and Chemistry

Publications

Harman, C. A., Rieke, C. J., Garavito, R. M., and Smith, W. L. Crystal structure of arachidonic acid bound to a mutant of Prostaglandin Endoperoxide Synthase-1 that forms predominantly 11-HPETE. J. Biol. Chem. (2004), 279: 42429-35.

Harman, C. A, Kozak, K. R, Marnett, L. J., Smith, W. L., and Garavito, R. M. Structural basis of enantioselective inhibition of COX-1 by (S)--substituted indomethacin ethanolamides. J. Biol. Chem. (2007), 282: 28096-28105.

Lim, P.J., Danner, R., Liang, J., Doong H., Harman, C., Srinivasan D., Rothenberg, C., Wang, H., Ye, Y., Fang, S., and Monteiro, M.J. Ubiquilin and p97/VCP bind Erasin, forming a complex involved in ERAD. J. Cell Biol. (2009), 187(2): 201-17.

Duan, H., Kachko, A., Zhong, L., Struble, Evi., Pandey S., Yan, H., Harman, C., Virata-Theimer, M.L., Deng, L., Zhao, Z., Major, M., Feinstone, S., & Zhang, P. Amino Acid Residue-Specific Neutralization and Non-Neutralization of Hepatitis C Virus by Monoclonal Antibodies to the E2 Protein (2012) J. Virology 86(23): 12686-94

Deng, L., Zhong, L., Struble, E., Ma, L., Harman, C., Yan, H., Virata-Theimer, M.L., Zhao, Z., Feinstone, S., Alter, H., & Zhang, P. Structural Evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus (2013) Proc Natl Acad Sci USA 110(18): 7418-22.

Harman, C., Zhong, L., Deng, L., Duan, Hongying, D., Zhong, Z., Ma, L., Liu, Peter., Struble, E., Yan, H., Feinstone, S., and Zhang, P. A View of the CD81-E2 Interface at the Binding Site of a Neutralizing Antibody against Hepatitis C Virus (in preparation 2013)

Build Your Own Now

DISCLAIMER

Resumes, and other information uploaded or provided by the user, are considered User Content governed by our Terms & Conditions. As such, it is not owned by us, and it is the user who retains ownership over such content.

Resume Overview

Companies Worked For:

  • FDA, Center of Biologics Evaluation and Research
  • Wright State University
  • Medical Biotechnology Center
  • Michigan State University
  • Purdue University
  • Mikart Inc
  • Eurand America
  • Southwestern Council for Higher Education

School Attended

  • Michigan State University
  • Wright State University

Job Titles Held:

  • Staff Fellow
  • Undergraduate Research Assistant
  • Postdoctoral Fellow
  • Postdoctoral Research Associate
  • Graduate Research Assistant
  • Analytical Chemist
  • Research Assistant

Degrees

  • Ph.D : Biochemistry and Molecular Biology , 2005
    B.S : Biology & Chemistry , 1996

Create a job alert for [job role title] at [location].

×

Advertisement

Similar Resumes

View All
Research-Chemist-/-Staff-Fellow-resume-sample

Research Chemist / Staff Fellow

Oak Ridge Institute for Science and Education ORISE

Little Rock, Arkansas

Administrative-Fellow-to-Chief-of-Medical-Staff-resume-sample

Administrative Fellow to Chief of Medical Staff

UAB Hospital

Birmingham, Alabama

Fellow-resume-sample

Fellow

Teach For India (Teach To Lead)

Fort Lauderdale, Florida

About
  • About Us
  • Privacy Policy
  • Terms of Use
  • Sitemap
Help & Support
  • Work Here
  • Contact Us
  • FAQs
Languages
  • EN
  • UK
  • ES
  • FR
  • IT
  • DE
  • NL
  • PT
  • PL
Customer Service
customerservice@livecareer.com
800-652-8430 Mon- Fri 8am - 8pm CST
Sat 8am - 5pm CST, Sun 10am - 6pm CST
  • Stay in touch with us
Site jabber winner award

© 2021, Bold Limited. All rights reserved.