Experienced scientific researcher with a wide-ranging skill set including a strong biochemistry and analytical chemistry background in addition to broad expertise in FDA regulation.
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Claire, C. A., Rieke, C. J., Garavito, R. M., and Smith, W. L. Crystal structure of arachidonic acid bound to a mutant of Prostaglandin Endoperoxide Synthase-1 that forms predominantly 11-HPETE. J. Biol. Chem. (2004), 279: 42429-35.
Claire, C. A, Kozak, K. R, Marnett, L. J., Smith, W. L., and Garavito, R. M. Structural basis of enantioselective inhibition of COX-1 by (S)--substituted indomethacin ethanolamides. J. Biol. Chem. (2007), 282: 28096-28105.
Lim, P.J., Danner, R., Liang, J., Doong H., Claire, C., Srinivasan D., Rothenberg, C., Wang, H., Ye, Y., Fang, S., and Monteiro, M.J. Ubiquilin and p97/VCP bind Erasin, forming a complex involved in ERAD. J. Cell Biol. (2009), 187(2): 201-17.
Duan, H., Kachko, A., Zhong, L., Struble, Evi., Pandey S., Yan, H., Claire, C., Virata-Theimer, M.L., Deng, L., Zhao, Z., Major, M., Feinstone, S., & Zhang, P. Amino Acid Residue-Specific Neutralization and Non-Neutralization of Hepatitis C Virus by Monoclonal Antibodies to the E2 Protein (2012) J. Virology 86(23): 12686-94
Deng, L., Zhong, L., Struble, E., Ma, L., Claire, C., Yan, H., Virata-Theimer, M.L., Zhao, Z., Feinstone, S., Alter, H., & Zhang, P. Structural Evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus (2013) Proc Natl Acad Sci USA 110(18): 7418-22.
Claire, C., Zhong, L., Deng, L., Duan, Hongying, D., Zhong, Z., Ma, L., Liu, Peter., Struble, E., Yan, H., Feinstone, S., and Zhang, P. A View of the CD81-E2 Interface at the Binding Site of a Neutralizing Antibody against Hepatitis C Virus (in preparation 2013)
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administrative fellow to chief of medical staff
UAB Hospital
Birmingham, Alabama
marie curie postdoctoral fellow
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)
Salt Lake City, Utah
postdoctoral fellow
National Center for Toxicological Research
Little Rock, Arkansas