postdoctoral research associate resume example with 14+ years of experience
Jessica
Claire
resumesample@example.com
(555) 432-1000,
, , 100 Montgomery St. 10th Floor
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Summary
An experienced cell and molecular biologist, passionate about leveraging strong research skills to bring novel therapies from bench to bedside, seeking an exciting role as a research scientist in the Biotech industry.
Skills
Meticulously design, perform and analyze cell biological and biochemical experiments with
Mammalian cell culture (C2C12 myoblasts and HEK cell lines).
Mutagenesis, Gel shift assays, and nucleic acid blotting (radioisotope labeled probe).
Education and Training
CSIR-CCMB Affiliated With Jawaharlal Nehru UniversityHyderabad, Expected in 2017 ā āPh.D:Life Sciences - GPA:
Panjab UniversityChandigarh, Expected in 07/2006 ā āMaster of Science:Biotechnology - GPA:
Himachal Pradesh UniversityShimla, Expected in 06/2004 ā āBachelor of Science: - GPA:
Experience
Wesleyan University - Postdoctoral Research Associate Middletown, CT, 07/2017 - 02/2022
Analyzed the underlying molecular mechanism of cobalamin deficiency associated with fetal developmental programming in a zebrafish model
Generated a tcn2 knockout zebrafish using
CRISPR/Cas9 technology and showed the observed phenotype of the mutants can be 2 ameliorated by supplementation of cobalamin during embryonic stages
Performed RNAseq analysis to uncover the different genetic pathways affected in the mutant embryos
Studied the role of a recently identified hexokinase Hkdc1 in the mice model
Independent genome-wide association studies in different populations have identified HKDC1 variants associated with elevated gestational 2-hr blood glucose levels in the third trimester
Performed molecular and functional characterization of Hkdc1 knockout mice model to understand its role in gestational and whole-body glucose homeostasis.
Kihomac - PhD Byron, GA, 02/2010 - 03/2017
Using Tol2 transgenesis, generated cardiac-specific transgenic zebrafish lines expressing GFP-tagged lamin A (WT/Mutant) and analyzed the effect of pathogenic lamin A mutations during embryonic development in homozygous zebrafish embryos
Transgenic zebrafish models of heart-specific laminopathies show cardiac regeneration, moderate deviation in heart rate, and misshapen nucleus in cardiomyocytes
Additionally, investigated the expression of zebrafish laminA promoter during embryonic development in transgenic reporter lines and by comparative expression of different deletion constructs of zebrafish lamin A promoter in vitro and in vivo
Identified a muscle-specific element in zebrafish lamin A promoter and a minimal promoter for zebrafish lamin A.
CSIR-CCMB - Project Assistant City, STATE, 03/2008 - 12/2009
Generated stable Ef1Ī±: GFP reporter zebrafish lines using Tol2 transgenesis
Cloning and phylogenetic analysis of the promoter and gene structure of myostatin from five members of cyprinids
Conducted transient expression assays in zebrafish embryos to study the tissue-specific activity of putative promoter fragments (Myostatin, Histone 3, Ī²-actin from different fish genera).
CSIR-Institute Of Genomics And Integrative Biology, Dr. S. Sivasubbu - Junior Research Fellow City, STATE, 07/2006 - 02/2008
Involved in the generation and screening of mutant zebrafish produced by the gene trap approach
Learned to set up and conduct a genetic screen and to characterize the insertion locus in transgenic animals
Participated in the large-scale mapping of Tol2 transposon integration sites in the zebrafish genome.
Accomplishments
Claire AD et al
Developmental programming of vitamin B12 deficiency model in zebrafish
(under preparation)
Claire AD and Parnaik VK
Heart-specific expression of laminopathic mutations in transgenic
zebrafish
Cell Biol Int
2017 Jul; 41(7):809-819
(PMID: 2846XXX2)
Claire AD and Parnaik VK
Identification of tissue-specific regulatory region in the
zebrafish lamin A promoter
Gene
2015 Aug 1; 567(1):73-80
(PMID: 25921963)
Poster Presentations
Claire AD et al
Generating zebrafish model of B12 deficiency
2nd
National Post Doc
Symposium, 2018, Hyderabad, India
Claire AD and Parnaik VK
Identification of tissue-specific regulatory region in the
zebrafish lamin A promoter
Indian Society of Developmental Biologists (InSDB), 2015,
Hyderabad, India
Claire AD and Parnaik VK
Regulation of tissue-specific expression of lamin A during
zebrafish development
InSDB, 2013, Mumbai, India
Awards
Senior research fellowship from the Council of Scientific and Industrial Research (CSIR), India
from 2012 to 2015
Junior research fellowship from CSIR, India from 2010 to 2012
Junior research fellowship from the Indian Council of Medical Research (ICMR), India
(declined, 2009)
Junior research fellowship (UGC) from CSIR, India 2006
Graduate Aptitude Test in Engineering (GATE) 2006 (All India Rank: 47).
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Resume Overview
School Attended
CSIR-CCMB Affiliated With Jawaharlal Nehru University