Accomplished scientific consultant with broad expertise in public health sector and scientific background in biomedical research and bioinformatics Expertise in clinical data standards, medical terminologies and controlled vocabularies used in healthcare data, including data modeling, semantics and semantic web technologies Experience in data management, including data integration, data mining in healthcare Strong management and organizational skills and ability to manage and lead large-scale, complex projects Experience in working with multiple stakeholders, including government, academics, and pharmaceutical companies. Strong, persuasive communication skills that build alliances, convey knowledge, strengthen relationships, and inspire teams. Ability to collaborate with all levels of professional, technical and support staff.
Ph.D., Chemistry1984Kanpur University/Central Drug Research Institute － Kanpur, India
Master of Science1977Lucknow University － Lucknow, India
Bachelor of Science, Biology1975Lucknow University － Lucknow, India
Ph.D. THESIS: (1984).Modification of some biochemical
changes in inflammation and their efficacy evaluation by non-steroidal
Management ConsultantMay 2008 to Current Booz Allen Hamilton － Rockville, MD
Management and planning support for clients in the federal health and science agencies Managing contract delivery (planning, content, reporting, financials, and placement) for providing support to National Children's Study.
Provided guidance for metadata development, data harmonization, consistent with the established and approved national and international standards to enable the collection, correlation, aggregation and linkage of semantically harmonized data across the study and with other networks.
Developed the terminology framework and established the foundation for a harmonized pediatric terminology to represent concepts associated with pediatrics in order provide the framework for semantic interoperability and increase collaborative clinical research and data sharing.
Provided support to plan and host conferences, to bring together the scientific research community to support coordination and communication across multiple pediatric terminology efforts.
Led the development of a prototype in partnership with the National Cancer Institute (NCI) to generate content-specific data acquisition tools for neonatal and infant examination; used UML modeling, annotation, and semantic integration tools to produce harmonized pediatric concepts and their corresponding data elements which were incorporated into NCI's metadata repository (caDSR).
Provided program management support for revision activities and establishing a governance plan for long term maintenance of Common Toxicity Criteria for Adverse Events (CTCAE) Terminology for the National Cancer Institute Center for Bioinformatics (NCI/CBITT).
Organized and implemented a governance structure and worked with a diverse stakeholder community in order to facilitate a comprehensive revision and review of the terminology.
Served as the key point of contact for all the revision activities.
Developed a prototype application tool to show how "omics" data (genotype/phenotype) in the National Database for Autism Research (NDAR) for Autism Spectrum Disorders can be efficiently integrated, queried and enriched by semantic technology and enable investigators to more easily identify associations between data, enriched data analysis and knowledge discovery.
Senior Scientist BioinformaticsSep 2004 to May 2008 Kevric, an IMC Company － Reston, VA
Project Management for vocabulary development for the Enterprise Vocabulary Services (EVS) project for National Cancer Institute Center for Bioinformatics (NCICB).
Responsibilities included reviewing and maintaining the quality of work performed on the project, including task assignment and coordination; functioning as a liaison between scientific domain experts and software programmers; collaborating with multi-organizations in terminology-related services; data standardization; semantic modeling using description logic modeling software and writing documents on modeling approaches.
Worked on NIH research portfolio analysis, the RCDC (Research, Condition and Disease Categories) project, for NIH budget reporting at OPASI/OD/NIH, to define disease category definitions and improve reliability & consistency of the NIH Health Research Portfolio and grants management, using natural language process technology to mine data from grant applications, research progress reports, project descriptions, using a knowledge management tool.
Human Disease Database: Project lead for integration of disease related genomic data from public resources into Celera database.
Designed and implemented the initial prototype database for mitochondrial genes.
Senior Scientist (Bioinformatics) Jun 2003 to Sep 2004 Celera Genomics － Rockville, MDHuman
Disease Database: Project lead for integration of disease related genomic data
from public resources into Celera database. Designed and implemented the
initial prototype database for mitochondrial genes.
Associate Research Scientist Dec 1991 to Jun 2003 Yale University － New Haven, CT
Microarray Database: Contributed towards the design and implementation of a
database for microarray research (YMD). Designed and implemented the initial
prototype database with a web based user interface (Keck ARray Manager and
Annotator (KARMA), a tool for comparing and annotating standard and custom
SPRAY Project: Worked as an
integral member on a collaborative research program to investigate the
inflammatory mechanisms that underlie isocyanate-induced asthma, in a laboratory
environment, in order to understand the pathogenesis of various forms of
asthma. This included identification of
diisocyanate bound carrier proteins in isocyanate asthma and studies on gene
expression from T-cells of HDI-asthmatics using human cDNA microarray
Fellowships and Awards
Junior Research Fellowship: Indian Council of Medical Research, India
Senior Research Fellowship: Indian Council of Medical Research, India
Research Associate: Council of Scientific and Industral Research, India
than 30 papers and abstracts. List can be made available upon request.
Health level 7
International Society of Computational
Project Management, Stakeholder engagement
& management, Data management, Data modeling, Data standards, Bioinformatics, Ontology, Controlled Vocabulary, Common data elements, Semantic