Structured researcher offering over 10-year background working in lab collecting, processing and analyzing various data. Versatile in multi-disciplinary involved in peptide drug design and development, including skills in biochemistry, organic chemistry, analytical chemistry and computational biology. Quality-focused professional recognized for performing all laboratory tests and procedures with attention to detail, optimum quality and expedience. Meanwhile, as the only PhD student in the group, acted also as lab manager for purchase and inventory of reagents, radiation safety, biohazard control and so on. Diligent and independent individual with in-depth knowledge of laboratory protocols and quality procedures. Impressive analytical, critical thinking and problem-solving skills.
Mentor: Victor J. Hruby
Publications during this period:
Yang Zhou, Saghar Mowlazadeh Haghighi, Zekun Liu, Lingzhi Wang, Victor J. Hruby, and Minying Cai*, Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 Receptor, ACS Pharmacology & Translational Science 2020
Liu X, Liu Z, Miao Y, Wang L, Yin H. Sex hormone-like Effects of Icariin on T-cells immune modulation in spontaneously hypertensive rats. J Ethnopharmacol. 2021 Apr 6;269:113717.
Attila Keresztes, Keith Olson, Paul Nguyen, Marissa A Lopez-Pier, Ryan Hecksel, Natalie K Barker, Zekun Liu, Victor Hruby, John Konhilas, Paul R Langlais, John M Streicher*, Antagonism of the Mu-Delta Opioid Receptor Heterodimer Enhances Opioid Anti-Nociception by Activating Src and CaMKII Signaling, Pain, 2021 Jul 9. doi: 10.1097/j.pain.0000000000002320
Papers under review:
Zekun Liu, Charls Alexander Page, Jose Luis Rios-Monterrosa, Yang Zhou, Samantha Zangari, Jonathan Sawyer, Tingyi Zhu, Kathia Antillon, Allysa Nordland, Victor Hruby, Minying Cai*, Design of novel human MC4R selective ligands and molecular mechanism studies of binding and activation via PWR.
Zekun Liu, Tingyi Zhu, Victor Hruby, Minying Cai*, Design of novel human MC5R selective ligands using multiple N-methylation.
Publication during the period:
Bonnie C. Carney, ZekunLiu, Abdulnaser Alkhalil, Taryn E. Travis, Lauren T. Moffatt, Jeffrey W. Shupp*, Elastin is Differentially Regulated by Pressure Therapy in A Porcine Model of Hypertrophic Scar, Journal of Burn Care and Research, Jan-2017, 38:28-35
Publications during the period:
Liu Zekun, Chen Haixia*. GC-MS Analysis of volatile oil from Bupleurum Chinese DC. f. vanheurckii (Muell.-Arg.) Shan et Y.LI. Journal of Medicinal Plants Research, 2012,6(5):926-928.
Liu Zekun, Chen Haixia*. GC-MS Analysis of Essential Oil from the Bark of Lindera obtusiloba. Chemistry of Natural Compounds, 2012, 48(4):696-697.
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