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Structured researcher offering over 10-year background working in lab collecting, processing and analyzing various data. Versatile in multi-disciplinary involved in peptide drug design and development, including skills in biochemistry, organic chemistry, analytical chemistry and computational biology. Quality-focused professional recognized for performing all laboratory tests and procedures with attention to detail, optimum quality and expedience. Meanwhile, as the only PhD student in the group, acted also as lab manager for purchase and inventory of reagents, radiation safety, biohazard control and so on. Diligent and independent individual with in-depth knowledge of laboratory protocols and quality procedures. Impressive analytical, critical thinking and problem-solving skills.
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Doble Engineering – Marlborough, MA,
- Participated in scar elastin research. Specifically, I'm responsible for studying on how pressure therapy affects scar elastin generation. Gene level and protein level expression of elastin was analyzed. Results were cheerful and paper was published together with other observations.
Basis.Ed – Washington, DC,
- During these years, I've taught general chemistry(CHEM151, CHEM152, CHEM 101) labs, organic(CHEM241, CHEM243)labs and tutoring biochemistry lectures(BIOC384, BIOC385), and being grader for all lecture parts of these courses
- Assisted teachers with classroom management and document coordination to maintain positive learning environment.
- Organized and guided activities for students, including skills practice, research and memorization tasks.
- Recorded grades for coursework and tests in online reporting system.
- Tutored struggling students individually and in small groups to reinforce learning concepts.
- Delivered personalized educational, behavioral and emotional support to individual students to enable positive learning outcomes.
Dlh Holdings Corp. – Falls Church, VA, China
- Participated opioid receptor drug discovery project. Synthesized and purified series of peptide derivatives for mu/kappa opioid receptors.
- Validated incoming data to check information accuracy and integrity while independently locating and correcting concerns.
- Developed macros, special formulas and other actions to produce reliable and consistent statistical reviews.
- Supported research and development efforts to create new products, equipment and processes.
- Prepared materials for reports, presentations and submission to peer-reviewed journal publications.
University of Arizona - Tucson, AZ
Mentor: Victor J. Hruby
Publications during this period:
Yang Zhou, Saghar Mowlazadeh Haghighi, Jessica Claire, Lingzhi Wang, Victor J. Hruby, and Minying Cai*, Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 Receptor, ACS Pharmacology & Translational Science XXX0
Claire X, Claire Z, Miao Y, Wang L, Yin H. Sex hormone-like Effects of Icariin on T-cells immune modulation in spontaneously hypertensive rats. J Ethnopharmacol. XXX1 Apr 6;269:113717.
Attila Keresztes, Keith Olson, Paul Nguyen, Marissa A Lopez-Pier, Ryan Hecksel, Natalie K Barker, Jessica Claire, Victor Hruby, John Konhilas, Paul R Langlais, John M Streicher*, Antagonism of the Mu-Delta Opioid Receptor Heterodimer Enhances Opioid Anti-Nociception by Activating Src and CaMKII Signaling, Pain, XXX1 Jul 9. doi: 10.1097/j.pain.0000000000002320
Papers under review:
Jessica Claire, Charls Alexander Page, Jose Luis Rios-Monterrosa, Yang Zhou, Samantha Zangari, Jonathan Sawyer, Tingyi Zhu, Kathia Antillon, Allysa Nordland, Victor Hruby, Minying Cai*, Design of novel human MC4R selective ligands and molecular mechanism studies of binding and activation via PWR.
Jessica Claire, Tingyi Zhu, Victor Hruby, Minying Cai*, Design of novel human MC5R selective ligands using multiple N-methylation.
Georgetown University - Washington, DC
Publication during the period:
Bonnie C. Carney, Jessica Claire, Abdulnaser Alkhalil, Taryn E. Travis, Lauren T. Moffatt, Jeffrey W. Shupp*, Elastin is Differentially Regulated by Pressure Therapy in A Porcine Model of Hypertrophic Scar, Journal of Burn Care and Research, Jan-2017, 38:28-35
Shandong University - China,
- Awarded the May 4th Young Scientist Prize 2014(top 4/10000)
- Awarded Excellent Program of The Sixth URTP(Undergraduate Research Training Program) 2012(top1/100)
- Awarded Excellent Student Cadres 2014(top 5/1000)
- Awarded Excellent Undergraduate Research Assistant 2012(top 15/1000)
- Received Academic Excellence Scholarship 2010(top 10/100)
- Received Social Work Scholarship 2011(top 6/1000)
- Member of student association
Publications during the period:
Claire Jessica, Chen Haixia*. GC-MS Analysis of volatile oil from Bupleurum Chinese DC. f. vanheurckii (Muell.-Arg.) Shan et Y.LI. Journal of Medicinal Plants Research, 2012,6(5):926-928.
Claire Jessica, Chen Haixia*. GC-MS Analysis of Essential Oil from the Bark of Lindera obtusiloba. Chemistry of Natural Compounds, 2012, 48(4):696-697.
- HONORS AND AWARDS , Shandong University May 4th Young Scientist Prize 2012(4/10000) University-level Excellent Program of The Sixth URTP 2012(1/100) University-level Excellent Undergraduate Research Assistant 2012(15/1000) Social Work Scholarship 2010(6/1000) University-level Excellent Student Cadres 2010(5/1000) Academic Excellence Scholarship 2010(10/100)
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School Attended
- University of Arizona
- Georgetown University
- Shandong University
Job Titles Held:
- Laboratory Technician
- Teaching Assistant
- Research Assistant
Degrees
- Ph.D.
- Master of Science
- Bachelor of Science
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