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Graduate Research Assistant Resume Example

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GRADUATE RESEARCH ASSISTANT
Summary

Ambitious student pursuing PhD in chemistry degree eager to contribute developed knowledge in medicinal and or process chemist role. Skilled in organic synthesis and protein chemistry in laboratory settings. Adaptable and driven with strong work ethic and ability to thrive in team-based or individually motivated settings.

Skills
  • Organic synthesis, catalysis and methodology development
  • Chemoenzymatic synthesis
  • Recombinant protein expression and purification
  • SAR, inhibitor design and synthesis
  • HPLC, LC-MS (ESI-MS, MS-MS), FPLC and affinity chromatography
  • Spectroscopic analysis (1D and 2D NMR, IR, UV-VIS)
  • Protein NMR studies and analysis
  • Protein X-ray crystallography, SDS-PAGE, gel electrophoresis
  • Assay development (Enzyme and cell based)
  • Vector and construct design, PCR, Cloning
  • Bio-informatics and protein-threading studies
  • Proficient working in glove box and handling air sensitive molecules
  • Independent design of experimental strategy, critical thinking and problem solving
  • Written and verbal communication skill
Research Experience
Graduate Research Assistant | 08/2016 to CurrentAssociation Of American Medical Colleges - Washington , DC

Mechanistic studies on THI5, a remarkable single turn-over enzyme that undergoes complex biochemical transformation to form pyrimidine core of Vitamin B1

  • Identified first catalytic intermediate in THI5 reaction by chemical rescue experiment, mutagenesis studies and small molecule mass spectrometric analysis.
  • Successfully characterized protein modification on THI5 enzyme by bottom-up proteomics , labeling studies and chemical model studies.
  • Designed and synthesized substrate analogs for biochemical characterization of intermediates in pathway of THI5 reaction.
  • Educated new graduate students on laboratory protocols and activities (includes organic and chemoenzymatic synthesis, protein overexpression and purification).
  • Maintained laboratory operations, that includes LC-MS (Bruker microToF Q-II) and HPLC (Agilent 1200, 1260 and 1290 infinity series) instrument supervising and managing.
Master of Science Thesis Work | 05/2015 to 04/2016IIT Kharagpur - City , STATE

Master's thesis on “Indole-C3-alkenylation and electrocyclization cascade for the synthesis of carbazole derivatives by triple relay catalysis”

  • Synthesizing carbazole natural product framework and applied novel catalysis to shorten the synthetic pathway.
  • Well-versed with name reactions like Swern oxidation, Fries Rearrangement, Wittig reaction and also used protecting group chemistry in course of target molecule synthesis
Winter Research Intern | 12/2014 to 01/2015IIT Kharagpur - City , STATE

Project on “Synthesis of functionalized benzoselenodiazole based precursor to develop D–p–A conjugated polymer for sensory application”

Education
Texas A&M University - - City,State | | Ph.D.Chemistry, Expected in 12/2021
  • Advisor - Prof. Tadhg P. Begley
  • GPA 3.54/4.0
IIT Kharagpur - - City | Master of ScienceChemistry, 07/2016
  • GPA 9.18/10.0
The University of Burdwan - - City | Bachelor of ScienceChemistry, 05/2014
  • Major in Chemistry
  • Minor in Physics and Mathematics
Publications
  • Mondal, A.; Yi-Lai, R.; Giri, N.; Begley, P. T. Cyano PLP–A Shunt Product in THI5 Reaction, Manuscript in preparation.
  • Ghosh, A. K.a; Samanta, I.a; Mondal,A.a; Liu, W. R. ChemMedChem,2019, 14, 889–906 (a = equal contribution). Highlighted in the cover feature of ChemMedChem, issue 9, May 2019.
  • Banerjee, A.; Guin, A.; Saha, S.;Mondal,A.; Maji, M. S.Org. Biomol. Chem.2019,17, 1822–1826. Selected as New Talentthemed issue.
Research Presentations
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at A. I. Scott Medal Symposium,2019, Chemistry Dept. Texas A&M University, College Station.
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at Dow Symposium,2019, Chemistry Dept. Texas A&M University, College Station.
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at Young Research Conference Aggieland,2019, Chemistry Dept. Texas A&M University, College Station.
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at1st Texas Chemical Biology Conference,2019, Chemistry Dept. Texas A&M University, College Station
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at1st Aggieland RNA Research Symposium,2019, Chemistry Dept. Texas A&M University, College Station.
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at 50thEnzyme Mechanism Conference,2019, New Orleans, LA.
  • Presented poster titled as “Thiamin Biosynthesis in Yeast: THI5 – A Remarkable Single turn-over Enzyme” at A. I. Scott Medal Symposium,2018, Chemistry Dept. Texas A&M University, College Station.
Professional and Scholastic Affiliations/Awards
  • Phi Lambda Upsilon Beta Beta Chapter at Texas A&M University- Member of Philanthropy and Volunteer Committees (April 2018-present)
  • Chemistry Student Safety Committee- Biological Division Representative (July 2019- present)
  • Organization for Cultural Diversity in Chemistry at Texas A&M University- Secretary (Aug 2019 - present)
  • Organization for Cultural Diversity in Chemistry at Texas A&M University- Historian (Aug 2018 - May 2019)
  • Graduate Student Association of Chemistry- Biological Division Representative (Aug 2018 - May 2019)
  • INSPIRE-SHE fellowship from The Department of Science and Technology, Government of India (Aug 2011 - July 2016)
Teaching
  • CHEM 234- Chemistry Major Organic Lab (Spring 2018-19)
  • CHEM 238- General Sophomore Organic Lab (Fall 2018-19)
  • CHEM 238- General Sophomore Organic Lab (Spring 2017-18)
  • CHEM 237- General Sophomore Organic Lab (Fall 2017-18)
  • CHEM 238- General Sophomore Organic Lab (Spring 2016-17)
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Resume Overview

School Attended

  • Texas A&M University
  • IIT Kharagpur
  • The University of Burdwan

Job Titles Held:

  • Graduate Research Assistant
  • Master of Science Thesis Work
  • Winter Research Intern

Degrees

  • Texas A&M University - City , State | Ph.D.
    IIT Kharagpur - City | Master of Science
    The University of Burdwan - City | Bachelor of Science

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