acting instructor resume example with 10+ years of experience
JessicaClaire
Montgomery Street, San Francisco, CA94105609 Johnson Ave., 49204, Tulsa, OK Home: (555) 432-1000 - Cell: - resumesample@example.com - : - -
Professional Summary
SUMMARY OF QUALIFICATIONS Medicinal Chemistry ~ Drug Design/Synthesis ~ Organic Synthesis Dedicated research scientist with Ph.D. in organic chemistry, post-doctoral and pharmaceutical company experience with a broad background of skills and expertise in protein/peptide chemistry, medicinal chemistry and organic synthesis solving complex research problems directly applicable to biotechnology and pharmaceutical industries. Demonstrated record of project success advancing knowledge through design, synthesis and characterization of small molecules, protein/peptide drug candidates and oligonucleotides. Outstanding project and team leader with collaborative relationship-building attributes.
Acting InstructorChurch & Dwight Co Inc – Mason City, IA,
Developed polypeptides with high zwitterion density as an efficient drug delivery vehicle for delivering drugs to the target site.
Key contributor in the development of zwitterionic polymer network encapsulation (ZPNE) technology to improve the stability, half-life and immunogenicity of therapeutic proteins.
Enhanced stability, half-life and immunogenicity of therapeutic proteins by zwitterionic nanogel encapsulation using newly synthesized phosophatidyl serine monomers.
Developed disulfide based carboxybetaine crosslinker for making degradable zwitterionic hydrogels for biomedical applications.
Developed novel zwitterionic monomers and crosslinkers for restraining the differentiation of stem cells using nonfouling zwitterionic hydrogels.
Developed coating-free non-fouling polymeric elastomer for fabricating biomedical devices in contact with biological media.
Developed new functional zwitterionic monomers for ultra-low fouling polymers.
01/2012 to 01/2013
Sr. Research ChemistBrigham And Women's Hospital – Milford, MA,
Led drug discovery research project encompassing design, synthesis and identification of lead peptidomimetic anticancer drug, MTI-101, for treatment of multiple myeloma.
Jessica Claire, Ph.D. PAGE 2 OF 2.
Optimized achievement of project goals by first designing a cyclic peptidomimetic scaffold utilizing a rational structure-based drug design approach and molecular modeling software.
Facilitated identification of lead drug candidate by performing complete structure-activity relationship (SAR) studies on the peptide scaffold.
Positioned lead peptide MTI-101 for commercialization as co-inventor on patent filing and by licensing IP to startup company Modulation Therapeutics, which is currently performing scale up.
Served as Principal Investigator on Phase I SBIR grant with NIH to carryout scale up of MTI-101.
Developed protocol for performing pharmacokinetics (PK) of MTI-101 using MRM technique.
Designed and developed novel peptoid-peptide hybrid scaffold for preparing focused combinatorial libraries for the discovery of protein-protein interaction inhibitors.
Involved in development of novel 18F labeled PET imaging agent.
01/2011 to 01/2012
Post-Doctoral Research ScientistH. LEE MOFFITT CANCER CENTER – City, STATE,
Innovated new synthetic routes for novel.
Turn promoters, as well as for making cyclic peptides on resin.
Reduced cost of large-scale cyclic peptide synthesis by devising 20gm pilot scale solid phase peptide synthesis, decreasing cost by 60%.
Leveraged success of multiple myeloma peptidomimetic, MTI-101, by designing inhibitors for p53-MDM2 and Rb-Raf-1 protein-protein interactions using this scaffold.
Expanded research capabilities by building collaborations with clinical biologists at the Moffitt Cancer Center to perform bioactivity assays and optimization studies on 70+ synthesized MTI-101analogs.
Valued as team leader mentoring 6 graduate and 8 undergraduate students, including assigning tasks and instructing team on how to design and synthesize protein-protein interactions inhibitors.
Education
Expected in 2010 to to
Ph.D: Organic Chemistry UNIVERSITY OF SOUTH FLORIDA - Tampa, FL GPA:
Dissertation: Design & Synthesis of
Hairpin Peptidomimetics for Modulating Integrin Mediated Cell Adhesion, Abeta Fibrillogenesis and p53-MDM2 Protein-Protein Interactions.
Advisor: Dr. Mark L. McLaughlin.
Expected in 2003 to to
MS Tech. Degree: Paints & Polymer Technology UNIVERSITY OF MUMBAI - , GPA:
Research Project Leadership Anticancer Drug Discovery Drug Molecule Design/Synthesis Lead Drug Candidate Identification Structure Activity Relationship (SAR) Solid Phase/Solution Phase Peptide Synthesis Oligonucleotide/Polymer Synthesis Pharmacokinetics (PK) Studies Bioconjugation PET Imaging Instrumental Methods/Molecular Characterization Team Building/Training Complex Problem Solving
Additional Information
HONORS AND RECOGNITION
, NIH Phase I SBIR grant award 2012
Travel Award, 22nd American Peptide Symposium, San Diego 2011
Served as Chairperson and reviewed 12 doctoral dissertations at USF 2011-2013
Tharpe Research Award, Department of Chemistry, USF 2006
Praharaj Memorial Award at UDCT, Mumbai 2003
Any information uploaded, such as a resume, or input by the user is owned solely by the user, not LiveCareer. For further information, please visit our Terms of Use.