Livecareer-Resume
JC
Jessica Claire
Montgomery Street, San Francisco, CA 94105 (555) 432-1000, resumesample@example.com
Summary
  • Experienced research scientist with a background in cellular radiobiology and cancer biology.
  • Well-versed in both benchtop and translational research.
  • Specialization in preclinical imaging techniques including PET/SPECT/CT, MRI, optical imaging as well as small animal irradiation.
Highlights
  • Preclinical image acquisition and analysis
  • Small animal models of cancer and other disease
  • Translational experimental design
  • Scientific publication and presentation preparation
Accomplishments

NIH Training Grant Awardee, Cancer Biology PhD Program, Wayne State University, Detroit, MI (2005-2007)

Radiation Research Society Scholar-in-Training Travel Award (2005, 2009)

Best Young Speaker, 2nd Symposium on Small Animal Radiotherapy, Vancouver, BC, Canada (2014)


Experience
02/2012 to Current Research Associate II Icon | Winston Salem, NC,

Management of a preclinical imaging area that includes a PET/SPECT/CT, 3-Tesla MRI, a near-infrared optical imager and an image-guided small animal irradiator.

Provides oversight and guidance for the planning and execution of small animal projects in Radiation Oncology and other departments in research institute.

07/2007 to 02/2012 Research Associate I, Department of Radiation Oncology William Beaumont Hospital | City, STATE,

Performed a variety of laboratory research including:

- in vitro response of prostate cells to radiation and dietary supplements

- in vivo impact of chemotherapy and radiation therapy during hypobaric oxygen treatment

- in vivo damage response pathways in hematopoietic stem cells after whole-body irradiation

- in vivo role of bone marrow-derived progenitor cells after radiation-induced lung damage

08/2002 to 07/2007 Graduate Research Assistant, Cancer Biology Graduate Program Wayne State University | City, STATE,

Completed research in pursuit of Ph.D. in cancer biology.

performed an array of laboratory techniques including cell survival assays, cell and yeast irradiation, flow cytometry, immunoflorescence and cell growth assays.

11/2001 to 07/2002 Research Assistant, Department of Pathology Wayne State University | City, STATE,

Conducted experiments in breast cancer research lab.

Techniques included bacterial transfection, cell cloning, western blotting, drug testing and invasion assays with human cancer cells.

Education
Expected in 2007 Ph.D. | Cancer Biology Wayne State University School of Medicine, Detroit, MI GPA:
Expected in 2002 Bachelor of Science | Biological Sciences Wayne State University, Detroit, MI GPA:
Professional Affiliations

Radiation Research Society

American Association of Cancer Research

American Society for Radiation Oncology

World Molecular Imaging Society

Publications

Peer-reviewed Manuscripts


Rajaganapathy BR, Janicki JJ, Levanovich P, Tyagi P, Hafron J, Chancellor MB, Claire SA and Marples B. Intravesical Liposomal Tacrolimus protects against radiation cystitis induced by 3-beam targeted bladder irradiation. J Urol. 2015 Aug;194(2):578-84.


Wobb J, Claire SA, Kane J, Galoforo S, Grills IS, Wilson GD and Marples B. The effects of pulsed radiotherapy on tumor oxygenation in two murine models of head and neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2015 Jul 15;92(4).

Dilworth JT, Claire SA, Wilson GD, Marples B. Preclinical models for translational research should maintain pace with modern clinical practice. IJROBP 1;88(3):540-4, March 2014.

Schoenherr D, Claire SA, Martin L, Marignol L, Wilson GD, Marples B. Determining if low dose hyper-radiosensitivity (HRS) can be exploited to provide a therapeutic advantage: A cell line study in four glioblastoma multiforme (GBM) cell lines. IJROBP. 89(12):1009-16, December 2013.

Kane J, Claire SA, Dilworth JT, Torma JT, Wilson GD, Marples B, Madlambayan GJ. Hematopoietic stem and progenitor cell migration after hypofractionated radiation therapy in a murine model. IJROBP. 87(5):1162-70, October 2013.

Lee DY, Chunta JL, Park SS, Huang J, Martinez AA, Grills IS, Claire SA, Wilson GD, Marples B. Pulsed verse conventional radion therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme. IJROBP. 86(5):978-85, August 2013.

Dilworth JT, Claire SA, Dabjan M, Grills IS, Torma J, Wilson GD, and Marples B. Pulsed Low-Dose Irradiation of Orthotopic Glioblastoma Multiforme (GBM) in a pre-clinical model: Effects on Vascularization and Tumor Control. Radiother. Oncol. 2013 Jun 19.

Swanson TA, Claire SA, Galoforo S, Thibodeau BJ, Martinez AA, Wilson GD, Marples B. TMPRSS2/ERG fusion gene expression alters chemo- and radio-responsiveness in cell culture models of androgen independent prostate cancer. The Prostate, 2011 Mar 10.

Claire SA, Wilson GD, Piasentin E, Joiner MC and Marples B. (2010). The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity. IJROBP 1;77(5):1509-17.
Claire SA, Collis SJ, Joiner MC, Wilson GD and Marples B. (2007). The transition in survival response from low-dose hyper-radiosensitivity (HRS) to increased radioresistance is independent of ATM Ser1981 activity. IJROBP 15;69(4): 1262-71.

Claire SA, Joiner MC, Weinfeld M, Piasentin E and Marples B. (2007). Role of apoptosis in low-dose hyper-radiosensitivity. Radiation Research 167 (3): 260-267.


Books and Chapters


SA Claire and GD Wilson. Flow cytometric DNA analysis of human cancers and cell lines. Methods Mol Biol 731:359-70, 2011.

B Marples, SA Claire, SJ Collis and MC Joiner. Low-dose hyper-radiosensitivity: A historical perspective. In Targeted Radionuclide Tumor Therapy (T. Stigbrand et al., Eds.), pp. 329-347. Springer Netherlands, 2008.

Skills

Translational experimental design

Small animal surgery and injections

IACUC protocol writing and review

Preclinical image acquisition and analysis (PET/CT/MRI/optical)

Small animal CT-guided radiation treatment planning and treatment

Radioactive material handling, documentation and transport

Cell culture

Western blotting and other protein analysis techniques

Flow cytometry staining and analysis

Flow and magnetic cell sorting

Immunofluoresence and immunohistochemistry staining and analysis of tissue and cell samples

Scientific paper, grant and professional presentation preparation

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School Attended

  • Wayne State University School of Medicine
  • Wayne State University

Job Titles Held:

  • Research Associate II
  • Research Associate I, Department of Radiation Oncology
  • Graduate Research Assistant, Cancer Biology Graduate Program
  • Research Assistant, Department of Pathology

Degrees

  • Ph.D.
  • Bachelor of Science

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