Project 1: Investigate the molecular mechanism by which SPRY2 and PBX1 regulates vascular tumors
Project 2: Functional characterization of primary human liver Angiosarcoma-derived endothelial cells.
Significance: Demonstrated the important growth regulatory roles of FOXO1/Sprouty2 and FOXO1/PBX1 pathway in vascular tumors that reveal potential new therapeutic strategies for these tumors by modulating and targeting this pathway.
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