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Postdoctoral Research Fellow Resume Example

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POSTDOCTORAL RESEARCH FELLOW
Summary

Ambitious Postdoctoral Research Fellow dedicated to Molecular Imaging research. Offering hands-on experience in supporting research efforts and completing independent projects. Eager to advance collective discipline knowledge and author high-quality scientific papers for publication in peer-reviewed journals.

Skills
  • Background in Organic Chemistry
  • Aseptic techniques
  • Proficient in Microsoft Office, GraphPad Prism, ChemDraw, SciFinder, Endnote, ImageJ
  • Team collaborations
  • Equipment maintenance
  • Recordkeeping Requirements
  • Bioassays
  • Lab Equipment Calibration
  • Proficient in biochemical assays (ELISAs, cell binding, flow cytometry)
  • Chemical, radioactive material and animal handling
  • Planning experiments
  • Report writing and publication
  • Research And Development
  • Chromatography
  • Equipment Management
    • Experience
    10/2018 to Current
    Postdoctoral Research FellowCompany Name － City, State
    • Proposed and implemented research focused on the development of peptide-based Positron Emission Tomography (PET) imaging agents
    • Conduct research on developing peptide-based Positron Emission Tomography PET imaging agents that target the Plectin-1 biomarker for Pancreatic Ductal Adenocarcinoma PDAC
    • Develop screening protocols based on magnetic microbead technology to identify novel plectin-1 binding peptides from an OBOC library
    • Evaluate SARS CoV2 spike protein-derived peptides for binding to integrins using ELISAs for the development of novel imaging/therapeutic agents for COVID-19
    • Lead the development and optimization of a novel integrin αvβ6 binding peptide from discovery OBOC library) to preclinical in vivo PET/CT imaging and biodistribution) studies
    • Adhered to all regulatory standards and university regulations for reporting
    • Presented findings at world-class research conferences
    • Produced well-written and thoroughly vetted research papers for industry journals
    • Craft protocols and reports pertaining to assay development and method validation
    07/2013 to 09/2018
    Graduate Research AssistantCompany Name － City, State
    • Provided research support and assisted in in vivo imaging and biodistribution studies
    • Executed radiochemical purity and specific activity determinations using radio-HPLC
    • Conducted in vitro assays ELISAs, flow cytometry, cell binding) to evaluate the binding profiles of peptide candidates to integrin αvβ6
    • Developed methods for purifying and characterizing samples for in vitro and preclinical studies using HPLC and MALDI TOF/MS
    • Performed peptide syntheses and modifications on solid-phase Implemented the on-bead two-color cell screening assay to expedite the manual screening process using fluorescent cell lines
    • Designed a highly focused one-bead one-compound OBOC 4 fluorobenzoyl peptide library targeting the integrin αvβ6.
    • Prepared tables, graphs, fact sheets and written reports summarizing research results.
    • Applied good documentation practices when recording data and managing source documentation.
    • Gave public presentations of findings at conferences.
    • Optimized equipment with calibration and maintenance to obtain accurate and precise results.
    09/2012 to 04/2016
    Graduate Teaching AssistantCompany Name － City, State
    • Instructed undergraduate students (upper division level) and assisted them with laboratory experiments, problem-solving, and instrumentation in organic chemistry courses
    • Educated undergraduate students on laboratory protocols and demonstrated laboratory experiments (distillation, flash chromatography, reflux) and instrumentation (HPLC, NMR, CD spectroscopy, IR, etc)
    • Performed instrument maintenance and troubleshooting, enforce safety policy and good laboratory practices
    • Proctored midterm and final exams, held office hours and attended lectures Evaluated and graded exams, lab reports, and papers.
    • Kept classroom focused on academic and intellectual discussions to further students' critical thinking skills as well as understanding of materials presented.
    • Adhered to university requirements for student assignments, testing and grading of work.
    • Followed established course outline to prepare lessons and convey information and enhance understanding of materials.
    • Tracked class and student metrics including attendance, projects, labs and reports.
    • Utilized email, phone and in-person meetings to answer questions and mentor struggling students.
    07/2011 to 07/2013
    Undergraduate/Graduate Research AssistantCompany Name － City, State
    • Designed and developed novel derivative of the integrin αvβ6 binding A20FMDV2 peptide to improve pharmacokinetics via incorporation of a silicon-containing amino acid
    • Synthesized, purified, and characterized enantioenriched 3 hydroxy- 2 allyl-oxindoles for publication Designed a library of isatin-containing small molecules and performed virtual screening using computational methods
    • Assisted with research for academic publications.
    Education and Training
    09/2020
    Graduate Program Certificate: Regulatory Affairs EssentialsUniversity Of California, San Diego － City
    • Completed coursework in Regulatory Requirements for Drugs and Biologics.
    09/2018
    Ph.D.: Organic ChemistryUniversity Of California, Davis － City

    Dissertation: Identification, Characterization and Development of novel Integrin αvβ6- targeting Peptide-based Imaging Agents for Positron Emission Tomography (PET)

    06/2012
    Bachelor of Science: Pharmaceutical ChemistryUniversity Of California, Davis － City
    • Magna cum laude graduate
    • Dean's List Honoree [Fall 2008 and Spring 2011]
    Publications

    S.H. Hausner, N. Bauer, R.A. Davis, T. Ganguly, Y. C. Tang, J. L. Sutcliffe. The Effects of an Albumin Binding Moiety on the Targeting and Pharmacokinetics of an integrin αvβ6-Selective Peptide Labeled with Aluminum [18F]Fluoride. Molecular Imaging and Biology. 2020

    T. Ganguly, Y. C. Tang, J .L. Sutcliffe. Evaluation of optical probes targeting the integrin αvβ6- in vitro, and in tumor-bearing mice. Molecular Imaging and Biology. 2020, 1-12

    Y. C. Tang, R. A. Davis, T. Ganguly, J.L. Sutcliffe. Identification, characterization and optimization of integrin αvβ6 –targeting peptides from a one-bead one-compound (OBOC) library: towards the development of positron emission tomography (PET) imaging agents. Molecules. 2019, 24(2), E309.

    N.V. Hanhan, Y. C. Tang, N.T. Tran, A. K. Franz. Scandium (III)-Catalyzed Enantioselective Allylation of Isatins Using Allylsilanes. Org. Lett. 2012, 14, 2218-2221.

    Patents

    · U.S. Patent 2019/0328910 A1 “Alpha(v)beta(6) integrin-binding peptides and methods of use thereof,” October 31, 2019.

    Presentations

    · Poster presentation: “Optimization of combinatorial library-derived peptides targeting the integrin αvβ6”. World Molecular Imaging Congress 2020, Virtual Meeting (October 2020)

    · Oral presentation: “Rapid identification and development of αvβ6 –targeting peptides as PET imaging agents using fluorescent cell-based on-bead screening”. Society of Nuclear Medicine and Molecular Imaging 2016 Annual Meeting, San Diego, CA (June, 2016)

    · Poster presentation: “Improving the high throughput screening process for the development of αvβ6-targeted PET imaging probes”. From Mouse to Men Symposium, Davis, CA (April, 2014)

    · Poster presentation: “Improving the high throughput screening process for the development of αvβ6-targeted PET imaging probes”. Miller Symposium, Davis, CA (March, 2014)

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    Resume Overview

    School Attended

    • University Of California, San Diego
    • University Of California, Davis

    Job Titles Held:

    • Postdoctoral Research Fellow
    • Graduate Research Assistant
    • Graduate Teaching Assistant
    • Undergraduate/Graduate Research Assistant

    Degrees

    • Graduate Program Certificate : Regulatory Affairs Essentials
      Ph.D. : Organic Chemistry
      Bachelor of Science : Pharmaceutical Chemistry

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