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Focused Graduate Student Researcher currently pursuing a degree in [Area of study] to advance research into [Area of expertise]. Self-motivated professional with excellent communication, planning and problem solving abilities.
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University of California, Los Angeles - Los Angeles, CA
In progress; started September 2018
University of California, Berkeley - Berkeley, CA
Biochemistry & Molecular Biology emphasis
Science and Mathematics Education Minor
Spanish Language & Literatures Minor
Penn State University – University Park, PA,
Professors Tomas Ganz & Elizabeta Nemeth (resumesample@example.coma.edu & resumesample@example.coma.edu) Investigate the molecular mechanism and pathological implications of the hepcidin-suppressing hormone erythroferrone (ERFE).
- Use biochemistry, molecular biology, and cell biology techniques to characterize the structural determinants of ERFE bioactivity.
- Analyze the BMP-binding abilities and preferences of human and murine ERFE and their physiological effects on iron homeostasis.
Study the sensitivities of various forms of ovarian cancer to ferroptosis—an iron-dependent, non-apoptotic form of programmed cell death.
- Use targeted cell culture-based systems to identify, measure, and characterize sensitivity to small molecule-induced ferroptosis in subsets of human ovarian cancers.
- Explore the molecular differences including signaling networks, cellular composition, and metabolic alterations that define responder and non-responder groups.
- Engineer modifications to molecule delivery systems with the goal of increasing therapeutic efficacy and translational potential.
UCLA – City, STATE,
- Fall Rotation: Dr. David Nathanson (resumesample@example.coma.edu) -Investigation into differential DNA damage profiles in glioblastoma cells as an indication of their ability to evade canonical apoptosis checkpoints.
- Winter Rotation: Drs. Tomas Ganz & Elizabeta Nemeth (resumesample@example.coma.edu & resumesample@example.coma.edu) - Investigation into the cause of cholesterol biosynthesis upregulation in endothelial cells treated with iron.
- Spring Rotation: Dr. Heather Christofk (resumesample@example.coma.edu) - Characterization of KHK-mediated tumor survival in hereditary leiomyomatosis and renal cell cancer.
UC Berkeley – City, STATE,
Professor Jamie Cate (resumesample@example.com) Investigated eIF4E3’s non-canonical role as a tumor suppressor during dysregulation of protein translation initiation.
- Used CRISPR-Cas9 in vitro and in vivo to edit the EIF4E3 gene in mouse cells.
- Established clonal populations of edited cells to be used for characterization.
Investigated independent translational regulation of the human ferritin light chain by iron and eIF3.
- Published in eLife: Repression of ferritin light chain translation by human eIF3 (2019).
- Mentor: Mia Pulos-Holmes (resumesample@example.com)
Ran independent project concerned with macrolide mechanisms of action (see 2016 SURF Fellow).
Worked in a group of four researchers on a Pfizer-collaboration project to discover a drug capable of stalling PCSK9 translation thereby lowering cholesterol.
- Performed biochemical assays to determine the motifs responsible for drug specificity.
- Mentor: Dr. Elizabeth Montabana (resumesample@example.com).
UC Berkeley – City, STATE,
UC Berkeley, Professor Jamie Cate (resumesample@example.com)
Led independent project uncovering the structural basis of macrolide function and eukaryotic resistance in the face of prokaryotic toxicity.
- Presented research at Berkeley Biophysics, Biochemistry, and Structural Biology Conference, Asilomar, January 2017.
- Presented research at Summer Undergraduate Research Fellowship Conference 2016, Berkeley, August 2016.
Rose Hills Undergraduate Research Fellowship 2016
For research proposed to study the molecular mechanisms of macrolides toward the discovery of new antibiotics
Cal Alumni Association Leadership Award 2015
For work with the American Cancer Society on the UC Berkeley campus
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School Attended
- University of California, Los Angeles
- University of California, Berkeley
Job Titles Held:
- Graduate Student Researcher
- First Year Graduate Rotations
- Undergraduate Researcher
- SURF Fellow
Degrees
- Ph.D.
- Bachelor of Arts
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