Detail-oriented scientist with ten years of medicinal chemistry experience and a proven track record of project contributions. A team-player and self-motivated enthusiast seeking a new opportunity to further knowledge in clinical science, and use skills in collaborative solution-driven problem solving to achieve project goals
Experienced synthetic organic and medicinal chemist with 10 years of experience within Oncology, GDC, working in diverse oncological programs preparing small molecule kinase inhibitors (IAP, CDK4, NIK, SHP2, PKC projects), macrocycles as in the Bcl-2 program and cyclic dinucleotides in Oncology Immunology (Sting program)
Track record of 16 publications in peer-reviewed journals and 7 patents.
Self-motivated chemist capable of independent work, prioritizing tasks and proactively sought collaborations with colleagues to achieve goals and further skills in problem-solving and effective team work
Initiated a collaboration with the OATS (OpenAccess Technology Systems) that is currently still ongoing to address issues encountered by chemists end-users in 2013, resulting in improvement of inter-departmental communications and instruments standardizations.
Proactively sought support from colleagues within ONC group to address support resources and in collaboration with the Separations and OATS groups to work on a plan to present alternative Contractor model to Leadership Team by end of 2015
Daily prioritization of tasks in the preparation, purification and isolation of multi-step syntheses in addition to planning synthetic routes, ordering reagents and preparing slides for presentation
Result-driven individual who meets deadlines in gram quantity scale-ups analogs for in vivo-studies in tight time schedules (examples: IAP, SHP2 and PKC)
Strong verbal and written communication skills
Trilingual individual, fluent in both English and French and spoken Cantonese
Basic written German and Spanish
Strong interpersonal skills derived from passion for multi-cultural diversity interactions
Attended Toastmasters sessions (not a member)
Regular presentations skills honed with projects and Oncology unit meetings
Team Work, Collaborations, Diversity & Inclusion:
Organized an MBTI (Myers-Briggs Type Indicator) workshop event for sub-group meeting as a creative alternative to welcome and learn about new colleagues from Emeryville and Horsham after their transfers to Onc-Cambridge
Regularly invite Analytical groups to give talk to Unit meetings to continuously foster collaborative effort between Oncology chemists and their support groups
Proactively sought Analytical expertise in a challenging purification of in-house synthesized CDN (cyclic dinucleotide), resulting in successful isolation of desired compound MDQ991
Synthetic organic chemist focusing on the design and preparation of novel medicines in the oncology disease area. Target designs driven by SAR and analysis of in-vitro and in-vivo data. Works in close collaborations with Analytical and Separation groups to improve efficiency of purification and isolation of challenging compounds. Self-motivated scientist who independently seeks new opportunity to further knowledge by attending in-house seminars and pursuing education in Clinical research.
Received a total of 15 NRG awards within the last three years for scientific impact, proactive inter-departmental collaborations and effective teamwork
Library design was chosen and awarded two NRG Star Awards (2014)
Was chosen by Executive Director of Oncology to propose a new Organizational Chart after new colleagues transferred from Emeryville and Horsham sites; led a team of four associates to work on proposal – received NRG Star Award (2014)
Addressing instrument support issues and promoting collaborations between OATS and Onc-chemists resulted in improvement of chemist work efficiency – received NRG Spot Award from Executive Director of Oncology (2013)
Detail-oriented and strong analytical skills resulted in discovering a vendor's sending the incorrect regioisomer starting material during SHP2 program, allowing project team members to avoid using incorrect intermediates that impacted a large scale library synthesis – received NRG Spot Award from project team leader (2011)
Was promoted from Scientific Associate II to Scientist I (2010)
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