Research Associate Resume Example

Motivated cancer biologist with over 10 years of research experience in multiple human-tumor malignancies with a focus on the identification and validation of oncogenes and on development of alternative therapeutic strategies for the treatment of cancer. Extensive experience with cell-based assays and in vivo models of diseases. Broad technical experience in cell biology, biochemistry, and molecular biology with proven ability to initiate interdisciplinary collaboration. Exceptional problem solving, communication, and multi tasking skills. Lentivirus/adenovirus preparation, transfection and infection Oral gavage, intravenous and intraperitoneal injection, animal dissection, bone marrow collection, tissue collection and processing for RNA and protein extraction, adenovirus delivery to mice by nasal administration Immunohistochemistry staining, immunofluorescence staining Protein expression and purification, immunoprecipitation, RT-PCR Cell proliferation assays, cell apoptosis assays, flow cytometry analysis using Flowjo, lineage depletion assay, colony formation assay in methylcellulose, primary cell culture Strong communication skills, experience in giving poster and oral presentations at international conferences.

Oral Zhou C, Martinez E, Di Marcantonio D, Aghayev T, Syeks SM (2015). X regulates ER stress signaling to promote chemoresistance in myeloid leukemia. In: 20th Annual Research Symposium at Fox Chase Cancer Center; Jun 2015; Philadelphia. Zhou C, Wong OG, Masters J, Williamson M (2009). Prostate cancer related mutations in Plexin-B1 affect RhoD signaling and cell function. In: Minisymposium in Cellular and Molecular Biology Session, 100th Annual Meeting of the American Association for Cancer Research; April 2009; Colorado. Poster Zhou C, Di Marcantonio D, Martinez E, Solanki-Tatel N, Peri S, Scholl C, Frohling S, Wiest DL, Sykes, SM (2015). X regulates ER stress signaling to promote chemotherapy resistance in acute myeloid leukemia. In: 57th ASH Annual Meeting and Exposition; December 2015; Florida (accepted). Zhou C, Ling MT, Lee TK, Man K, Wang X, Wong YC (2005). FTY720, a fungus metabolite, inhibits invasion ability of androgen independent prostate cancer cells through inactivation of RhoA-GTPase. In: 96th Annual Meeting of the American Association for Cancer Research; April 2005; California. ACADEMIC PUBLICATIONS Zhou C, Di Marcantonio D, Martinez E, Solanki-Tatel N, Peri S, Scholl C, Frohling S, Wiest DL, Sykes, SM. X regulates ER stress signaling to promote chemotherapy resistance in acute myeloid leukemia. Manuscript in preparation. Frax597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. J Biol Chem. 2013 Oct 4;288(40): 29105-14. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Shoe LC, Liu Q, Vachiani A, Albelda SM, Kissil JL. Oncogene. 2013 Feb 14;32(7):903-9. Effects of cancer-associated mutations in the PlexinB1 gene. Zhou C, Wong OG, Masters J, Williamson M. Mol Cancer. 2012 Mar 9;11(1):11. Plexin-B1 mutations in prosate cancer. Wong OG, Nitkunan T, Oinuma I, Zhou C, Blanc V, Brown RS, Bott SR, Nariculam J, Box G, Munson P, Constantinou J, Feneley MR, Klocker H, Eccles SA, Negishi M, Freeman A, Masters JR, Williamson M. Proc Natl Acad Sci USA. 2007 Nov 27;104(48): 19040-5. FTY720, a fungus metabolite, inhibits invasion ability of androgen-independent prostate cancer cells through inactivation of RhoA-GTPase. Zhou C, Ling MT, Lee TK, Man K, Wang X, Wong YC. Cancer Lett. 2006 Feb 20;233(1):36-47. Overexpression of Id-1 in prostate cancer cells promotes angiogenesis through activation of vascular endothelial growth factor (VEGF). Ling MT, Lau TC, Zhou C, Chua CW, Kwok WK, Wang X, Wong YC. Carcinogenesis. 2005 Oct 26;(10):1668-76. Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target Kwok WK, Ling MT, Lee TW, Lau TC, Zhou C, Zhang X, Chua CW, Chan KW, Chan FL, Glackin C, Wong YC, Wang X. Cancer Res. 2005 Jun 15;65(12):5153-62. FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer. Chua CW, Lee DT, Ling MT, Zhou C, Man K, Ho J, Chan FL, Wang X, Wong YC. Int J Cancer. 2005 Dec 20;117(6):1039-48.

Biology, cancer, experiments, features, imaging, inventory, novel, protocols, express, ras, Research, transcription, type 2