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Postdoctoral Fellow Resume Example

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POSTDOCTORAL FELLOW
Accomplishments
  • Inflammation and chronic kidney disease A.
  • Personal Statement I am currently a postdoctoral fellow in the Laboratory of Dr.
  • Ganesan Ramesh in Vascular Biology Center at Georgia Health Sciences University.
  • The focus of the current research project is to understand the anti-inflammatory role of netrin-1 in the acute and chronic kidney disease model.
  • My academic training and research experience so far have provided me with an excellent background in multiple biological disciplines including molecular biology and biochemistry, especially in the field of inflammation.
  • In my master's graduation project, I partially purified and characterized the key inflammatory enzyme phospholipase A2 (PLA2) from Indian cobra (Naja naja) venom.
  • As a predoctoral student, my main research work was to derivatize hydrophilic antioxidants to a hydrophobic molecule without affecting its antioxidant activity and study its therapeutic aspect against snake venom and inflammatory PLA2 induced inflammation.
  • Through this study we have obtained several interesting results, which leads to publications in peer reviewed journals.
  • Further, in my postdoctoral training, I have continued my inflammation research in the acute and chronic kidney disease model.
  • We used specific transgenic and knockout animals and cell lines to understand the role and regulation of endogenous anti-inflammatory molecule, Netrin-1 in acute and chronic kidney diseases.
  • Current research led to publications in peer-reviewed journals and our findings have also been discussed in the recent edition of Nature Review Nephrology.
  • We are also studying the effect and regulation of cytokine IL17 in diabetic nephropathy and in different type of fibrosis model.
  • As a postdoctoral fellow, I have the required expertise and positive motivation with specific training to successfully carry out the assigned project.
  • B.
  • Positions and Honors Positions and Employment 2005 - 2007 Trainee Scientist, CAS-Bio Project, Jubilant Biosys Pvt Ltd.
  • Mysore, India.
  • 2007 - 2008 Guest Faculty, Biochemistry Department, University of Mysore, India 2011 - Present Post Doctoral Fellow, Vascular Biology Center, Georgia Health Sciences University, Augusta, Georgia.
Experience
01/2001Company Name
09/2010 to 09/2015Company Name
  • Netrin-1 signaling in ischemia reperfusion injury of the kidney.
  • Major Goal(s): To determine the mechanisms whereby netrin-1 production is regulated and the mechanism whereby netrin-1 protects kidney epithelial cells against ischemia reperfusion injury.
Postdoctoral Fellow, 07/2013 to 07/2015Company Name
  • Regulation of Inflammation by Netrin-1 in Diabetic Nephropathy.
  • Major Goal(s): To determine.
  • Role: Principal Investigator of Postdoctoral Fellowship Grant.
  • PHS 398/2590 (Rev.
  • 06/09) Page Biographical Sketch Format Page.
Education
B.S:MM/YY,06/03University of Mysore － City, IndiaBegin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) INSTITUTION AND LOCATION MM/YY
M.S:08/05Biochemistry University of Mysore － City, India
Ph.D:02/11Biochemistry University of Mysore － City, India
Georgia Health Sciences University － City, StateMohamed R, Ranganathan P, Jayakumar C, Nauta FL, Gansevoort RT, Weintraub NL, Brands M, Ramesh G. Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice. J Mol Med (Berl). 2014 Dec;92(12):1245-56. doi: 10.1007/s00109-014-1209-3. Epub 2014 Sep 25. PMID: 25249008. Ranganathan P, Mohamed R, Jayakumar C, Ramesh G. Guidance cue netrin-1 and the regulation of inflammation in acute and chronic kidney disease.Mediators Inflamm. 2014;2014:525891. doi: 10.1155/2014/525891. Epub 2014 Jun 3. Review. PMID: 24991088. Ranganathan P, Jayakumar C, Mohamed R, Weintraub NL, Ramesh G. Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol. 2014 Jul 15;307(2):F183-94. doi: 10.1152/ajprenal.00177.2014. Epub 2014 May 14. PMID: 24829504. Mohamed R, Tarannum S, Yariswamy M, Vivek HK, Siddesha JM, Angaswamy N, Vishwanath BS. Ascorbic acid 6-palmitate: a potent inhibitor of human and soybean lipoxygenase-dependent lipid peroxidation. J Pharm Pharmacol. 2014 Jun;66(6):769-78. doi: 10.1111/jphp.12200. Epub 2013 Dec 22. PMID: 24359271. White JJ, Mohamed R, Jayakumar C, Ramesh G. Tubular injury marker netrin-1 is elevated early in experimental diabetes. J Nephrol. 2013 Nov-Dec;26(6):1055-64. doi: 10.5301/jn.5000303. Epub 2013 Aug PMID: 24052471. Mohamed R, Jayakumar C, Ramesh G. Chronic administration of EP4-selective agonist exacerbates albuminuria and fibrosis of the kidney in streptozotocin-induced diabetic mice through IL-6. Lab Invest. 2013 Aug;93(8):933-45. doi: 10.1038/labinvest.2013.85. PMID: 23817085. Mohamed R, Jayakumar C, Ranganathan PV, Ganapathy V, Ramesh G. Kidney Proximal Tubular Epithelial-Specific Overexpression of Netrin-1 Suppresses Inflammation and Albuminuria through Suppression of COX-2-Mediated PGE2 Production in Streptozotocin-Induced Diabetic Mice. Am J Pathol. 2012 Dec;181(6):1991-2002. doi: 10.1016/j.ajpath.2012.08.014. Epub 2012 Oct 2. PMCID: PMC3509740. Ranganathan PV, Jayakumar C, Mohamed R, Ramesh G. Netrin-1 regulates inflammatory response of neutrophils and macrophages by suppressing COX-2-mediated PGE2 production and suppresses ischemic acute kidney injury. Kidney Int. 2012. PMC Journal - In Process. Jayakumar C, Mohamed R, Ranganathan PV, Ramesh G. Intracellular kinases mediate increased translation and secretion of netrin-1 from renal tubular epithelial cells. PLoS One. 2011;6(10):e26776. doi: 10.1371/journal.pone.0026776. Epub 2011 Oct 26. PMCID: PMC3202578. Tarannum S, Mohamed R, Vishwanath BS. Inhibition of testicular and Vipera russelli snake venom hyaluronidase activity by Butea monosperma (Lam) Kuntze stem bark. Nat Prod Res. 2012;26(18):1708-11. doi: 10.1080/14786419.2011.602829. Epub 2011 Oct 19. PMID: 22007959. Mohamed R, Shivaprasad HV, Jameel NM, Shekar MA, Vishwanath BS. Neutralization of local toxicity induced by vipera russelli phospholipase A2 by lipophilic derivative of ascorbic acid. Curr Top Med Chem. 2011;11(20):2531-9. PMID: 21682683. Abdu Musad E, Mohamed R, Saeed BA, Vishwanath BS, Rai KM. Synthesis and evaluation of antioxidant and antibacterial activities of new substituted bis(1,3,4-oxadiazoles), 3,5-bis(substituted) pyrazoles and isoxazoles. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3536-40. doi: 10.1016/j.bmcl.2011.04.142. Epub 2011 May 6. PMID: 21612921. Mohamed R, Dharmappa KK, Tarannum S, Jameel NM, Kannum SA, Ashrafulla HS, Rai L, Souza CJ, Shekhar MA, Vishwanath BS. Chemical modification of ascorbic acid and evaluation of its lipophilic derivatives as inhibitors of secretory phospholipase A(2) with anti-inflammatory activity. Mol Cell Biochem. 2010 Dec;345(1-2):69-76. doi: 10.1007/s11010-010-0561-z. Epub 2010 Aug 22. PMID: 20730622. Dharmappa KK, Mohamed R, Shivaprasad HV, Vishwanath BS. Genistein, a potent inhibitor of secretory phospholipase A2: a new insight in down regulation of inflammation. Inflammopharmacology. 2010 Feb;18(1):25-31. doi: 10.1007/s10787-009-0018-8. Epub 2009 Nov 6. PMID: 19894024. Shivaprasad HV, Riyaz M, Venkatesh Kumar R, Dharmappa KK, Tarannum S, Siddesha JM, Rajesh R, Vishwanath BS. Cysteine proteases from the Asclepiadaceae plants latex exhibited thrombin and plasmin like activities. J Thromb Thrombolysis. 2009 Oct;28(3):304-8. doi: 10.1007/s11239-008-0290-2. Epub 2008 Nov 1. Dharmappa KK, Kumar RV, Nataraju A, Mohamed R, Shivaprasad HV, Vishwanath BS. Anti-inflammatory activity of oleanolic acid by inhibition of secretory phospholipase A2. Planta Med. 2009 Feb;75(3):211-5. doi: 10.1055/s-0028-1088374. Epub 2008 Dec 11. PMID: 19085684.
Interests
Principal Investigator/Program Director (Last, First, Middle): BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME Fnu Riyaz Mohamed POSITION TITLE Postdoctoral Fellow eRA COMMONS USER NAME (credential, e.g., agency login) R_MOHAMED
Professional Affiliations
2012 Member, American Heart Association (AHA) 2011 Member, American Society of Nephrology (ASN) 2009 Member, Biochemistry Research Organization 2007 Member, Society of Biological Chemists (India) 2005 Member, Biochemical Society, Mysore Chapter Honors
Publications
Ranganathan P, Mohamed R, Jayakumar C, Ramesh G Deletion of UNC5B in kidney epithelium exacerbates diabetic nephropathy in mice. 2015.American Journal of Nephrology (Accepted).
Additional Information
  • Principal Investigator/Program Director (Last, First, Middle): BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME Fnu Riyaz Mohamed POSITION TITLE Postdoctoral Fellow eRA COMMONS USER NAME (credential, e.g., agency login) R_MOHAMED
Skills
acid 6, acid, BA, C, Dec, derivatives, MA, nursing, Oct, Oct 2, Page, translation
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Resume Overview

School Attended

  • University of Mysore
  • Biochemistry University of Mysore
  • Georgia Health Sciences University

Job Titles Held:

  • Postdoctoral Fellow

Degrees

  • B.S : MM/YY , 06/03
    M.S : 08/05
    Ph.D : 02/11

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